Ashwinikumar Kulkarni
Overview
Explore the profile of Ashwinikumar Kulkarni including associated specialties, affiliations and a list of published articles.
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23
Citations
4369
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Recent Articles
21.
Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, et al.
Nature
. 2015 Feb;
518(7539):317-30.
PMID: 25693563
The reference human genome sequence set the stage for studies of genetic variation and its association with human disease, but epigenomic studies lack a similar reference. To address this need,...
22.
Sephton C, Tang A, Kulkarni A, West J, Brooks M, Stubblefield J, et al.
Proc Natl Acad Sci U S A
. 2014 Oct;
111(44):E4769-78.
PMID: 25324524
The RNA-binding protein fused-in-sarcoma (FUS) has been associated with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), two neurodegenerative disorders that share similar clinical and pathological features. Both missense...
23.
Xie W, Schultz M, Lister R, Hou Z, Rajagopal N, Ray P, et al.
Cell
. 2013 May;
153(5):1134-48.
PMID: 23664764
Epigenetic mechanisms have been proposed to play crucial roles in mammalian development, but their precise functions are only partially understood. To investigate epigenetic regulation of embryonic development, we differentiated human...
24.
Osborne J, Larsen J, Shields M, Gonzales J, Shames D, Sato M, et al.
Proc Natl Acad Sci U S A
. 2013 Apr;
110(16):6524-9.
PMID: 23553831
Small-cell lung cancer and other aggressive neuroendocrine cancers are often associated with early dissemination and frequent metastases. We demonstrate that neurogenic differentiation 1 (NeuroD1) is a regulatory hub securing cross...
25.
Ma X, Kulkarni A, Zhang Z, Xuan Z, Serfling R, Zhang M
Nucleic Acids Res
. 2012 Jan;
40(7):e50.
PMID: 22228832
Identification of DNA motifs from ChIP-seq/ChIP-chip [chromatin immunoprecipitation (ChIP)] data is a powerful method for understanding the transcriptional regulatory network. However, most established methods are designed for small sample sizes...