Ashwini Hinge
Overview
Explore the profile of Ashwini Hinge including associated specialties, affiliations and a list of published articles.
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11
Citations
345
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Recent Articles
1.
Javier J, Hinge A, Bartram J, Xu J, Filippi M
Haematologica
. 2021 Oct;
107(6):1323-1334.
PMID: 34706493
Bone marrow failure syndromes are characterized by ineffective hematopoiesis due to impaired fitness of hematopoietic stem cells. They can be acquired during bone marrow stress or innate and are associated...
2.
Hinge A, He J, Bartram J, Javier J, Xu J, Fjellman E, et al.
Cell Stem Cell
. 2020 Feb;
26(3):420-430.e6.
PMID: 32059807
The metabolic requirements of hematopoietic stem cells (HSCs) change with their cell cycle activity. However, the underlying role of mitochondria remains ill-defined. Here we found that, after mitochondrial activation with...
3.
Lee J, Govindarajah V, Goddard B, Hinge A, Muench D, Filippi M, et al.
J Exp Med
. 2017 Dec;
215(2):627-644.
PMID: 29282250
Obesity is a chronic organismal stress that disrupts multiple systemic and tissue-specific functions. In this study, we describe the impact of obesity on the activity of the hematopoietic stem cell...
4.
Hinge A, Filippi M
Curr Stem Cell Rep
. 2017 May;
2(4):388-397.
PMID: 28529843
The hematopoietic system is highly dynamic and must constantly produce new blood cells every day. Mature blood cells all derive from a pool of rare long-lived hematopoietic stem cells (HSCs)...
5.
Hinge A, Xu J, Javier J, Mose E, Kumar S, Kapur R, et al.
Nat Commun
. 2017 Feb;
8:14382.
PMID: 28176763
The mechanisms regulating hematopoietic stem and progenitor cell (HSPC) fate choices remain ill-defined. Here, we show that a signalling network of p190-B RhoGAP-ROS-TGF-β-p38 balances HSPC self-renewal and differentiation. Upon transplantation,...
6.
Yang J, Kalim K, Li Y, Zhang S, Hinge A, Filippi M, et al.
J Allergy Clin Immunol
. 2015 Jun;
137(1):231-245.e4.
PMID: 26100081
Background: Mitochondrial metabolism is known to be important for T-cell activation. However, its involvement in effector T-cell differentiation has just begun to gain attention. Importantly, how metabolic pathways are integrated...
7.
Kumar S, Ciraolo G, Hinge A, Filippi M
J Immunol Methods
. 2013 Dec;
404:87-90.
PMID: 24291346
Transmission electron microscopy (TEM) provides ultra-structural details of cells at the sub-organelle level. However, details of the cellular ultrastructure, and the cellular organization and content of various organelles in rare...
8.
Bajaj M, Hinge A, Limaye L, Gupta R, Surolia A, Kale V
Glycobiology
. 2010 Nov;
21(4):521-9.
PMID: 21106560
We have recently demonstrated that the mannose-binding lectins, namely banana lectin (BL) and garlic lectin (GL), interacted with the insulin receptors on M210B4 cells--an established mesenchymal cell line of murine...
9.
Hinge A, Bajaj M, Limaye L, Surolia A, Kale V
Stem Cells Dev
. 2009 Jul;
19(2):163-74.
PMID: 19580456
Lectins form an important constituent of our daily diet, and thus, it is essential that their effect(s) on various tissues be examined systematically in order to assess whether they are...
10.
Ranjekar P, Hinge A, Hegde M, Ghate M, Kale A, Sitasawad S, et al.
Psychiatry Res
. 2003 Dec;
121(2):109-22.
PMID: 14656446
Oxidative stress-mediated cell damage has been considered in the pathophysiology of schizophrenia. Abnormal findings have often been considered related to differences in ethnicity, life style, dietary patterns and medications, all...