Ashton N Combs
Overview
Explore the profile of Ashton N Combs including associated specialties, affiliations and a list of published articles.
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5
Citations
33
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0
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Recent Articles
1.
Benn G, Borrelli C, Prakaash D, Johnson A, Fideli V, Starr T, et al.
Proc Natl Acad Sci U S A
. 2024 Dec;
121(50):e2416426121.
PMID: 39630873
OmpA, a predominant outer membrane (OM) protein in , affects virulence, adhesion, and bacterial OM integrity. However, despite more than 50 y of research, the molecular basis for the role...
2.
Combs A, Silhavy T
Annu Rev Microbiol
. 2024 Jul;
78(1):191-211.
PMID: 39008906
Envelope biogenesis and homeostasis in gram-negative bacteria are exceptionally intricate processes that require a multitude of periplasmic chaperones to ensure cellular survival. Remarkably, these chaperones perform diverse yet specialized functions...
3.
Combs A, Silhavy T
Proc Natl Acad Sci U S A
. 2021 Dec;
119(1).
PMID: 34969846
The biogenesis of integral β-barrel outer membrane proteins (OMPs) in gram-negative bacteria requires transport by molecular chaperones across the aqueous periplasmic space. Owing in part to the extensive functional redundancy...
4.
Murray L, Combs A, Rekapalli P, Cristea I
Methods Enzymol
. 2019 Oct;
626:587-620.
PMID: 31606092
Lysine acetylation is a prevalent posttranslational modification that acts as a regulator of protein function, subcellular localization, and interactions. A growing body of work has highlighted the importance of temporal...
5.
Liu Y, Palmer S, Chang H, Combs A, Burne R, Koo H
Environ Microbiol Rep
. 2017 Nov;
10(1):12-22.
PMID: 29124888
Streptococcus mutans strongly influences the development of pathogenic biofilms associated with dental caries. Our understanding of S. mutans behaviour in biofilms is based on a few well-characterized laboratory strains; however,...