Ashraf M Khalil
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Explore the profile of Ashraf M Khalil including associated specialties, affiliations and a list of published articles.
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5
Citations
206
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Recent Articles
1.
Nicoletti A, Kenny C, Khalil A, Pan Q, Ralph K, Ritchie J, et al.
J Pharmacol Exp Ther
. 2016 Jul;
359(1):37-44.
PMID: 27440419
Therapeutic agents antagonizing B-cell-activating factor/B-lymphocyte stimulator (BAFF/BLyS) are currently in clinical development for autoimmune diseases; belimumab is the first Food and Drug Administration-approved drug in more than 50 years for...
2.
Khalil A, Dotimas H, Kahn J, Lamerdin J, Hayes D, Gupta P, et al.
J Pharmacol Exp Ther
. 2016 Jun;
358(3):423-30.
PMID: 27340210
Growth differentiation factor-11 (GDF11) and myostatin (MSTN) are highly related transforming growth factor-β (TGF-β) ligands with 89% amino acid sequence homology. They have different biologic activities and diverse tissue distribution...
3.
Duke J, Liu M, Yaari G, Khalil A, Tomayko M, Shlomchik M, et al.
J Immunol
. 2013 Mar;
190(8):3878-88.
PMID: 23514741
Aberrant targeting of the enzyme activation-induced cytidine deaminase (AID) results in the accumulation of somatic mutations in ≈ 25% of expressed genes in germinal center B cells. Observations in Ung(-/-)...
4.
Khalil A, Cambier J, Shlomchik M
Science
. 2012 May;
336(6085):1178-81.
PMID: 22555432
Germinal centers (GCs) generate memory B and plasma cells, which are essential for long-lived humoral immunity. GC B cells with high-affinity B cell receptors (BCRs) are selectively expanded. To enable...
5.
Khalil A, Nakahara K, Tokuriki M, Kaseda Y, Murakami N
J Vet Med Sci
. 2009 Sep;
71(8):1075-8.
PMID: 19721361
On Misaki peninsula, Japan, fecal samples were collected from 14 Misaki stallions at monthly intervals for 12 consecutive months. The fecal testosterone concentration was measured by radioimmunoassay. We examined monthly...