Ashraf El-Meanawy
Overview
Explore the profile of Ashraf El-Meanawy including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
252
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Recent Articles
1.
Goorani S, Khan A, Mishra A, El-Meanawy A, Imig J
Kidney Blood Press Res
. 2024 Jan;
49(1):69-80.
PMID: 38185105
Introduction: Renal fibrosis is a critical event in the development and progression of chronic kidney disease (CKD), and it is considered the final common pathway for all types of CKD....
2.
Waldman M, Sinaii N, Lerma E, Kurien A, Jhaveri K, Uppal N, et al.
Kidney360
. 2023 Mar;
4(3):349-362.
PMID: 36996301
No abstract available.
3.
Imig J, Hye Khan M, Stavniichuk A, Jankiewicz W, Goorani S, Yeboah M, et al.
Biochem Pharmacol
. 2023 Jan;
210:115438.
PMID: 36716827
The incidence of ureter obstruction is increasing and patients recovering from this kidney injury often progress to chronic kidney injury. There is evidence that a long-term consequence of recovery from...
4.
Lack of xanthine dehydrogenase leads to a remarkable renal decline in a novel hypouricemic rat model
Dissanayake L, Zietara A, Levchenko V, Spires D, Burgos Angulo M, El-Meanawy A, et al.
iScience
. 2022 Aug;
25(9):104887.
PMID: 36039296
Uric acid (UA) is the final metabolite in purine catabolism in humans. Previous studies have shown that the dysregulation of UA homeostasis is detrimental to cardiovascular and kidney health. The...
5.
Rinschen M, Palygin O, El-Meanawy A, Domingo-Almenara X, Palermo A, Dissanayake L, et al.
Nat Commun
. 2022 Jul;
13(1):4099.
PMID: 35835746
Hypertension and kidney disease have been repeatedly associated with genomic variants and alterations of lysine metabolism. Here, we combined stable isotope labeling with untargeted metabolomics to investigate lysine's metabolic fate...
6.
Al Ammary F, Yu S, Muzaale A, Segev D, Liyanage L, Crews D, et al.
Transpl Int
. 2021 Jun;
34(8):1530-1541.
PMID: 34129713
Allografts from living kidney donors with hypertension may carry subclinical kidney disease from the donor to the recipient and, thus, lead to adverse recipient outcomes. We examined eGFR trajectories and...
7.
Miller B, Palygin O, El-Meanawy A, Mattson D, Geurts A, Staruschenko A, et al.
Life Sci
. 2021 Jun;
279:119661.
PMID: 34087282
Aims: Adaptor protein p66Shc, encoded by Shc1 gene, contributes to the pathogenesis of oxidative stress-related diseases. p66Shc ability to promote oxidative stress-related diseases requires phosphorylation of serine 36 residue (Ser36)...
8.
Golosova D, Palygin O, Bohovyk R, Klemens C, Levchenko V, Spires D, et al.
Life Sci Alliance
. 2020 Oct;
3(12).
PMID: 33046522
Opioid use is associated with predictors of poor cardiorenal outcomes. However, little is known about the direct impact of opioids on podocytes and renal function, especially in the context of...
9.
Srivastava T, Joshi T, Jiang Y, Heruth D, Rezaiekhaligh M, Novak J, et al.
Am J Physiol Renal Physiol
. 2020 Jul;
319(2):F312-F322.
PMID: 32628542
The ultrafiltrate flow over the major processes and cell body generates fluid flow shear stress (FFSS) on podocytes. Hyperfiltration-associated increase in FFSS can lead to podocyte injury and detachment. Previously,...
10.
Srivastava T, Ju W, Milne G, Rezaiekhaligh M, Staggs V, Alon U, et al.
Prostaglandins Other Lipid Mediat
. 2019 Dec;
146:106403.
PMID: 31838197
Introduction: Hyperfiltration is a major contributor to progression of chronic kidney disease (CKD) in diabetes, obesity and in individuals with solitary functioning kidney (SFK). We have proposed hyperfiltration-induced injury as...