Ashok B Shenvi
Overview
Explore the profile of Ashok B Shenvi including associated specialties, affiliations and a list of published articles.
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4
Citations
30
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0
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Recent Articles
1.
Zhang M, Zhou D, Wang Y, Maier D, Widzowski D, Sobotka-Briner C, et al.
J Pharmacol Exp Ther
. 2011 Aug;
339(2):567-78.
PMID: 21825000
The preclinical pharmacology and pharmacokinetic properties of (2R)-6-methoxy-8-(4-methylpiperazin-1-yl)-N-(4-morpholin-4-ylphenyl)chromane-2-carboxamide (AZD3783), a potent 5-hydroxytryptamine 1B (5-HT(1B)) receptor antagonist, were characterized as part of translational pharmacokinetic/pharmacodynamic hypothesis testing in human clinical trials. The...
2.
Luo X, Krumrine J, Shenvi A, Pierson M, Bernstein P
J Mol Graph Model
. 2010 Aug;
29(3):372-81.
PMID: 20800520
We present a technique for computing activity discriminants of in vitro (pharmacological, DMPK, and safety) assays and the application to the prediction of in vitro activities of proposed synthetic targets...
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Tian G, Ghanekar S, Aharony D, Shenvi A, Jacobs R, Liu X, et al.
J Biol Chem
. 2003 Apr;
278(31):28968-75.
PMID: 12719412
Transition state analogs pepstatin methylester (PME) and L685458 have been shown to inhibit gamma-secretase non-competitively (Tian, G., Sobotka-Briner, C., Zysk, J., Liu, X., Birr, C., Sylvester, M. A., Edwards, P....