Asbjorn Holmgren
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Explore the profile of Asbjorn Holmgren including associated specialties, affiliations and a list of published articles.
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21
Citations
447
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Recent Articles
1.
Holmgren A, Akkouh I, OConnell K, Osete J, Bjornstad P, Djurovic S, et al.
Mol Psychiatry
. 2024 Feb;
29(4):1128-1138.
PMID: 38351171
Bipolar disorder is a severe neuro-psychiatric condition where genome-wide association and sequencing studies have pointed to dysregulated gene expression as likely to be causal. We observed strong correlation in expression...
2.
Misceo D, Senaratne L, Mero I, Sundaram A, Bjornstad P, Szczaluba K, et al.
Genes (Basel)
. 2023 Nov;
14(11).
PMID: 38002928
Strømme syndrome is an ultra-rare primary ciliopathy with clinical variability. The syndrome is caused by bi-allelic variants in CENPF, a protein with key roles in both chromosomal segregation and ciliogenesis....
3.
Gamage T, Grabmayr H, Horvath F, Fahrner M, Misceo D, Louch W, et al.
Sci Signal
. 2023 Feb;
16(771):eadd0509.
PMID: 36749824
Stormorken syndrome is a multiorgan hereditary disease caused by dysfunction of the endoplasmic reticulum (ER) Ca sensor protein STIM1, which forms the Ca release-activated Ca (CRAC) channel together with the...
4.
Holmgren A, Hansson L, Bjerkaas-Kjeldal K, Impellizzeri A, Gilfillan G, Djurovic S, et al.
Transl Psychiatry
. 2022 Jan;
12(1):45.
PMID: 35091539
The gene ankyrin-3 (ANK3) has been consistently associated with bipolar disorder (BD) in several genome-wide association studies (GWAS). The exact molecular mechanisms underlying this genetic association remain unknown. The discovery...
5.
Epting D, Senaratne L, Ott E, Holmgren A, Sumathipala D, Larsen S, et al.
Hum Mutat
. 2020 Nov;
41(12):2179-2194.
PMID: 33131181
Ciliopathies are clinically and genetically heterogeneous diseases. We studied three patients from two independent families presenting with features of Joubert syndrome: abnormal breathing pattern during infancy, developmental delay/intellectual disability, cerebellar...
6.
Gamage T, Lengle E, Gunnes G, Pullisaar H, Holmgren A, Reseland J, et al.
Cell Calcium
. 2019 Dec;
85:102110.
PMID: 31785581
Calcium signaling plays a central role in bone development and homeostasis. Store operated calcium entry (SOCE) is an important calcium influx pathway mediated by calcium release activated calcium (CRAC) channels...
7.
Akkouh I, Skrede S, Holmgren A, Ersland K, Hansson L, Bahrami S, et al.
Neuropsychopharmacology
. 2019 Oct;
45(6):947-955.
PMID: 31652432
Lithium has been the first-line treatment for bipolar disorder (BD) for more than six decades. Although the molecular effects of lithium have been studied extensively and gene expression changes are...
8.
Gamage T, Gunnes G, Lee R, Louch W, Holmgren A, Bruton J, et al.
Cell Calcium
. 2018 Nov;
76:87-100.
PMID: 30390422
STIM1 and ORAI1 regulate store-operated Ca entry (SOCE) in most cell types, and mutations in these proteins have deleterious and diverse effects. We established a mouse line expressing the STIM1...
9.
Hughes T, Sonderby I, Polushina T, Hansson L, Holmgren A, Athanasiu L, et al.
Transl Psychiatry
. 2018 Oct;
8(1):210.
PMID: 30297702
Ankyrin-3 (ANK3) is one of the few genes that have been consistently identified as associated with bipolar disorder by multiple genome-wide association studies. However, the exact molecular basis of the...
10.
Stromme P, Groeneweg S, Lima de Souza E, Zevenbergen C, Torgersbraten A, Holmgren A, et al.
Thyroid
. 2018 Oct;
28(11):1406-1415.
PMID: 30296914
Background: Thyroid hormones (TH) are essential for brain development and function. The TH transporters monocarboxylate transporter 8 (MCT8) and organic anion transporter1 C1 (OATP1C1) facilitate the transport of TH across...