Asami Oji
Overview
Explore the profile of Asami Oji including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
681
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0
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Recent Articles
1.
Takahashi S, Kyogoku H, Hayakawa T, Miura H, Oji A, Kondo Y, et al.
Nature
. 2024 Aug;
633(8030):686-694.
PMID: 39198647
Faithful DNA replication is essential for genome integrity. Under-replicated DNA leads to defects in chromosome segregation, which are common during embryogenesis. However, the regulation of DNA replication remains poorly understood...
2.
Oji A, Choubani L, Miura H, Hiratani I
Curr Opin Cell Biol
. 2024 Jul;
90:102406.
PMID: 39083950
Mammalian chromosomes form a hierarchical structure within the cell nucleus, from chromatin loops, megabase (Mb)-sized topologically associating domains (TADs) to larger-scale A/B compartments. The molecular basis of the structures of...
3.
Sulekh S, Ikegawa Y, Naito S, Oji A, Hiratani I, Yoo S
Life Sci Alliance
. 2024 Jan;
7(4).
PMID: 38296349
Cell death and proliferation are at a glance dichotomic events, but occasionally coupled. Caspases, traditionally known to execute apoptosis, play non-apoptotic roles, but their exact mechanism remains elusive. Here, using...
4.
Yamaguchi K, Chen X, Oji A, Hiratani I, Defossez P
Cancers (Basel)
. 2022 May;
14(10).
PMID: 35625988
Epigenetic abnormalities are extremely widespread in cancer. Some of them are mere consequences of transformation, but some actively contribute to cancer initiation and progression; they provide powerful new biological markers,...
5.
Fujihara Y, Lu Y, Noda T, Oji A, Larasati T, Kojima-Kita K, et al.
Proc Natl Acad Sci U S A
. 2020 Apr;
117(17):9393-9400.
PMID: 32295885
Sperm-oocyte fusion is a critical event in mammalian fertilization, categorized by three indispensable proteins. Sperm membrane protein IZUMO1 and its counterpart oocyte membrane protein JUNO make a protein complex allowing...
6.
Oji A, Isotani A, Fujihara Y, Castaneda J, Oura S, Ikawa M
Biol Reprod
. 2020 Jan;
102(4):975-983.
PMID: 31916570
In mammals, more than 2000 genes are specifically or abundantly expressed in testis, but gene knockout studies revealed several are not individually essential for male fertility. Tesmin (Metallothionein-like 5; Mtl5)...
7.
Fujihara Y, Noda T, Kobayashi K, Oji A, Kobayashi S, Matsumura T, et al.
Proc Natl Acad Sci U S A
. 2019 Aug;
116(37):18498-18506.
PMID: 31455729
CRISPR/Cas9-mediated genome editing technology enables researchers to efficiently generate and analyze genetically modified animals. We have taken advantage of this game-changing technology to uncover essential factors for fertility. In this...
8.
Lu Y, Oura S, Matsumura T, Oji A, Sakurai N, Fujihara Y, et al.
Biol Reprod
. 2019 Jun;
101(2):501-511.
PMID: 31201419
More than 1000 genes are predicted to be predominantly expressed in mouse testis, yet many of them remain unstudied in terms of their roles in spermatogenesis and sperm function and...
9.
Shide K, Kameda T, Kamiunten A, Oji A, Ozono Y, Sekine M, et al.
Blood Cancer J
. 2019 Mar;
9(4):42.
PMID: 30926777
Calreticulin (CALR) exon 9 frameshift mutations, commonly detected in essential thrombocythemia (ET) and primary myelofibrosis patients, activate signal transducer and activator of transcription (STAT) proteins in the presence of Myeloproliferative...
10.
Fujihara Y, Oji A, Kojima-Kita K, Larasati T, Ikawa M
J Cell Sci
. 2018 Sep;
131(19).
PMID: 30209135
Chemokines are signaling proteins that are secreted to induce chemotaxis during an immunological response. However, the functions of transmembrane-type chemokine-like factor (CKLF) and the CMTM (CKLF-like MARVEL transmembrane domain containing)...