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Asad Jan

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Articles 37
Citations 901
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Recent Articles
1.
Theologidis V, Ferreira S, Jensen N, Gomes Moreira D, Ahlgreen O, Hansen M, et al.
Acta Neuropathol Commun . 2025 Feb; 13(1):32. PMID: 39962601
α-Synuclein (aSyn) accumulation within the extra-nigral neuronal populations in the brainstem, including the gigantocellular nuclei (GRN/Gi) of reticular formation, is a recognized feature during the prodromal phase of Parkinson disease...
2.
Grondin A, Natividad M, Ogata T, Jan A, Gaudin A, Trijatmiko K, et al.
Rice (N Y) . 2024 Apr; 17(1):25. PMID: 38592643
Background: Development of transgenic rice overexpressing transcription factors involved in drought response has been previously reported to confer drought tolerance and therefore represents a means of crop improvement. We transformed...
3.
Gomes Moreira D, Jan A
Sci Data . 2023 Jul; 10(1):432. PMID: 37414779
The discovery of surrogate biomarkers reflecting neuronal dysfunction in neurodegenerative diseases (NDDs) remains an active area of research. To boost these efforts, we demonstrate the utility of publicly available datasets...
4.
Jan A, Hayat M, Wedyan M, Alturki R, Gazzawe F, Ali H, et al.
Comput Biol Med . 2022 Nov; 151(Pt A):106311. PMID: 36410097
Antimicrobial peptides (AMPs) are gaining a lot of attention as cutting-edge treatments for many infectious disorders. The effectiveness of AMPs against bacteria, fungi, and viruses has persisted for a long...
5.
Ilyas M, Hussain Shah S, Fujita Y, Maruyama K, Nakashima K, Yamaguchi-Shinozaki K, et al.
Plant Signal Behav . 2022 Nov; 17(1):2142725. PMID: 36398733
Different abiotic stresses induce , a tandem CCCH-type zinc finger domain gene, in rice. Here, we report that transgenic rice plants overexpressing under own promoter (OX [for overexpression]) transferred to...
6.
Monti G, Gomes Moreira D, Richner M, Mutsaers H, Ferreira N, Jan A
Cells . 2022 Jul; 11(13). PMID: 35805109
Defects in brain energy metabolism and proteopathic stress are implicated in age-related degenerative neuronopathies, exemplified by Alzheimer's disease (AD) and Parkinson's disease (PD). As the currently available drug regimens largely...
7.
Ferreira N, Richner M, van der Laan A, Jul Christiansen I, Vaegter C, Nyengaard J, et al.
Brain Commun . 2022 Apr; 4(2):fcac067. PMID: 35386219
[This corrects the article DOI: 10.1093/braincomms/fcab104.].
8.
Richner M, Goncalves N, Jensen P, Nyengaard J, Vaegter C, Jan A
STAR Protoc . 2022 Mar; 3(1):101181. PMID: 35243373
This protocol outlines a minimally invasive and quickly performed approach for transgene delivery in the extracranial nervous system of adult mice using recombinant adeno-associated virus (AAV). The technique, named Sciatic...
9.
Jan A, Goncalves N, Vaegter C, Jensen P, Ferreira N
Int J Mol Sci . 2021 Aug; 22(15). PMID: 34361100
The pathological aggregation of the presynaptic protein α-synuclein (α-syn) and propagation through synaptically coupled neuroanatomical tracts is increasingly thought to underlie the pathophysiological progression of Parkinson's disease (PD) and related...
10.
Ferreira N, Richner M, van der Laan A, Jul Christiansen I, Vaegter C, Nyengaard J, et al.
Brain Commun . 2021 Jun; 3(2):fcab104. PMID: 34136810
Neuropathological observations in neurodegenerative synucleinopathies, including Parkinson disease, implicate a pathological role of α-synuclein accumulation in extranigral sites during the prodromal phase of the disease. In a transgenic mouse model...