Arunasalam Naguleswaran
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Explore the profile of Arunasalam Naguleswaran including associated specialties, affiliations and a list of published articles.
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43
Citations
718
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Recent Articles
1.
Sivabalakrishnan K, Hemphill A, Karunaratne S, Naguleswaran A, Roditi I, Surendran S, et al.
Med Vet Entomol
. 2025 Mar;
PMID: 40052247
Aedes aegypti L. and Aedes albopictus Skuse mosquitoes (Diptera: Culicidae), the principal vectors of many human arboviral diseases, lay eggs and undergo preimaginal development in fresh water. They have recently...
2.
Inglebert M, Dettwiler M, He C, Markkanen E, Opitz L, Naguleswaran A, et al.
Vet Sci
. 2025 Feb;
12(2).
PMID: 40005944
High-throughput omics approaches have long been used to uncover potential vulnerabilities in human personalized oncology but are often limited by the lack of functional validation. Therefore, we placed our emphasis...
3.
Etzensperger R, Benninger M, Pozzi B, Rehmann R, Naguleswaran A, Schumann G, et al.
mBio
. 2024 Dec;
16(2):e0337524.
PMID: 39688410
Importance: We have established a procedure to permanently label pairs of trypanosomes that transiently fuse their flagella and exchange proteins. When this occurs, a reporter gene is permanently flipped from...
4.
Maurizio M, Masid M, Woods K, Caldelari R, Doench J, Naguleswaran A, et al.
Nat Commun
. 2024 Jul;
15(1):6145.
PMID: 39034325
Parasitic diseases, particularly malaria (caused by Plasmodium falciparum) and theileriosis (caused by Theileria spp.), profoundly impact global health and the socioeconomic well-being of lower-income countries. Despite recent advances, identifying host...
5.
Bruhlmann F, Perry C, Griessen C, Gunasekera K, Reymond J, Naguleswaran A, et al.
mBio
. 2024 May;
15(6):e0341223.
PMID: 38747635
is a tick-transmitted apicomplexan parasite that gained the unique ability among parasitic eukaryotes to transform its host cell, inducing a fatal cancer-like disease in cattle. Understanding the mechanistic interplay between...
6.
Ajiboye J, Uldry A, Heller M, Naguleswaran A, Fan E, Van Voorhis W, et al.
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38473953
is an apicomplexan parasite causing persistent diarrhea in humans and animals. Issuing from target-based drug development, calcium-dependent protein kinase 1 inhibitors, collectively named bumped kinase inhibitors (BKIs), with excellent efficacies...
7.
Smith Jr J, Tylec B, Naguleswaran A, Roditi I, Read L
mBio
. 2023 Oct;
14(5):e0185423.
PMID: 37795988
is the unicellular parasite that causes African sleeping sickness and nagana disease in livestock. The parasite has a complex life cycle consisting of several developmental forms in the human and...
8.
Pozzi B, Naguleswaran A, Florini F, Rezaei Z, Roditi I
Nucleic Acids Res
. 2023 Apr;
51(10):5177-5192.
PMID: 37070196
TbMex67 is the major mRNA export factor known to date in trypanosomes, forming part of the docking platform within the nuclear pore. To explore its role in co-transcriptional mRNA export,...
9.
Shaw S, Knusel S, Abbuhl D, Naguleswaran A, Etzensperger R, Benninger M, et al.
Nat Commun
. 2022 Feb;
13(1):603.
PMID: 35105902
The collective movement of African trypanosomes on semi-solid surfaces, known as social motility, is presumed to be due to migration factors and repellents released by the parasites. Here we show...
10.
Naguleswaran A, Fernandes P, Bevkal S, Rehmann R, Nicholson P, Roditi I
PLoS Negl Trop Dis
. 2021 Sep;
15(9):e0009504.
PMID: 34543277
Trypanosoma brucei ssp., unicellular parasites causing human and animal trypanosomiasis, are transmitted between mammals by tsetse flies. Periodic changes in variant surface glycoproteins (VSG), which form the parasite coat in...