Arthur Yi Loong Sim
Overview
Explore the profile of Arthur Yi Loong Sim including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
128
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0
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Recent Articles
1.
Chua K, Sim A, Yeo E, Bin Masroni M, Naw W, Leong S, et al.
Int J Mol Sci
. 2023 Mar;
24(5).
PMID: 36902186
There is an increasing urgency in the search for new drugs to target high-grade cancers such as osteosarcomas (OS), as these have limited therapeutic options and poor prognostic outlook. Even...
2.
Chua K, Virshup D, Odono E, Chang K, Tan N, Hue S, et al.
Pathology
. 2020 Nov;
53(2):229-238.
PMID: 33187685
Overexpression of WLS, an upstream protein in the Wnt pathway, has been implicated in several non-osteogenic tumours. This study represents the first attempt at evaluating WLS expression in various bone...
3.
Novera W, Lee Z, Nin D, Dai M, Idres S, Wu H, et al.
Antioxid Redox Signal
. 2020 Apr;
33(17):1191-1208.
PMID: 32336105
Current treatment options for ovarian clear cell carcinoma (OCCC) are limited to combination of platinum-based and other cytotoxic agents to which patients respond poorly due to intrinsic chemoresistance. There is...
4.
Tan H, Sim A, Long Y
Nat Commun
. 2017 Aug;
8(1):338.
PMID: 28835610
Activation of autophagy and elevation of glutamine synthesis represent key adaptations to maintain amino acid balance during starvation. In this study, we investigate the role of autophagy and glutamine on...
5.
Wan Z, Tian J, Tan H, Chow A, Sim A, Ban K, et al.
Hepatology
. 2016 May;
64(4):1289-301.
PMID: 27178107
Unlabelled: Fibroblast growth factor 19 (FGF19) is an important postprandial enterokine which regulates liver metabolism and hepatocyte proliferation. However, the precise mechanism by which FGF19 regulates these cellular effects is...
6.
Tan H, Sim A, Huang S, Leng Y, Long Y
J Mol Endocrinol
. 2015 Sep;
55(3):197-207.
PMID: 26373795
Exercise enhances numerous signalling pathways and activates substrate metabolism in skeletal muscle. Small molecule compounds that activate these cellular responses have been shown to recapitulate the metabolic benefits of exercise....