Arthur C-K Chung
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Explore the profile of Arthur C-K Chung including associated specialties, affiliations and a list of published articles.
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12
Citations
568
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Recent Articles
1.
Chung A, Lan H
Front Physiol
. 2015 Mar;
6:50.
PMID: 25750628
MicroRNAs (miRNAs) are endogenous short non-coding RNAs that regulate most of important cellular processes by inhibiting gene expression through the post-transcriptional repression of their target mRNAs. In kidneys, miRNAs have...
2.
Lan H, Chung A
Semin Nephrol
. 2012 Jul;
32(3):236-43.
PMID: 22835454
Chronic progressive kidney diseases typically are characterized by active renal fibrosis and inflammation. Transforming growth factor-β1 (TGF-β1) is a key mediator in the development of renal fibrosis and inflammation. TGF-β1...
3.
Gu P, Xu X, Le Menuet D, Chung A, Cooney A
Stem Cells
. 2011 May;
29(7):1041-51.
PMID: 21608077
The pluripotency gene Oct4 encodes a key transcription factor that maintains self-renewal of embryonic stem cell (ESC) and is downregulated upon differentiation of ESCs and silenced in somatic cells. A...
4.
Gu P, Le Menuet D, Chung A, Cooney A
Mol Cell Biol
. 2009 Mar;
29(7):1987.
PMID: 19279189
No abstract available.
5.
Lan Z, Xu X, Chung A, Cooney A
Biol Reprod
. 2009 Jan;
80(5):905-12.
PMID: 19164181
Nuclear receptor subfamily 6, group A, member 1 (NR6A1) is an orphan member of the nuclear receptor superfamily and is required for normal mouse embryonic development. In adult mice, NR6A1...
6.
Chung A, Zhou S, Liao L, Tien J, Greenberg N, Xu J
Cancer Res
. 2007 Jun;
67(12):5965-75.
PMID: 17575167
Although the amplified-in-breast cancer 1 (AIB1; SRC-3, ACTR, or NCoA3) was defined as a coactivator for androgen receptor (AR) by in vitro studies, its role in AR-mediated prostate development and...
7.
Gu P, Le Menuet D, Chung A, Cooney A
Mol Cell Biol
. 2006 Oct;
26(24):9471-83.
PMID: 17030610
The pluripotent factor Oct4 is a key transcription factor that maintains embryonic stem (ES) cell self-renewal and is down-regulated upon the differentiation of ES cells and silenced in somatic cells....
8.
Chung A, Xu X, Niederreither K, Cooney A
Dev Biol
. 2006 Mar;
293(1):13-24.
PMID: 16530751
The isthmic organizer, which is located at the midbrain-hindbrain boundary, is important for midbrain development. The mechanism by which the development of the organizer is initiated and maintained is not...
9.
Gu P, LeMenuet D, Chung A, Mancini M, Wheeler D, Cooney A
Mol Cell Biol
. 2005 Sep;
25(19):8507-19.
PMID: 16166633
Embryonic stem (ES) cell pluripotency and differentiation are controlled by a network of transcription factors and signaling molecules. Transcription factors such as Oct4 and Nanog are required for self-renewal and...
10.
Gu P, Goodwin B, Chung A, Xu X, Wheeler D, Price R, et al.
Mol Cell Biol
. 2005 Apr;
25(9):3492-505.
PMID: 15831456
Oct4 plays an essential role in maintaining the inner cell mass and pluripotence of embryonic stem (ES) cells. The expression of Oct4 is regulated by the proximal enhancer and promoter...