Arpita Upadhyaya
Overview
Explore the profile of Arpita Upadhyaya including associated specialties, affiliations and a list of published articles.
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59
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1362
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Recent Articles
1.
Fettweis G, Wagh K, Stavreva D, Jimenez-Panizo A, Kim S, Lion M, et al.
bioRxiv
. 2024 Dec;
PMID: 39713324
While the cohesin complex is a key player in genome architecture, how it localizes to specific chromatin sites is not understood. Recently, we and others have proposed that direct interactions...
2.
Johnson T, Fettweis G, Wagh K, Ceacero-Heras D, Krishnamurthy M, Sanchez de Medina F, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(47):e2413737121.
PMID: 39541347
The glucocorticoid and mineralocorticoid receptors (GR and MR, respectively) have distinct, yet overlapping physiological and pathophysiological functions. There are indications that both receptors interact functionally and physically, but the precise...
3.
Pathni A, Wagh K, Rey-Suarez I, Upadhyaya A
J Cell Sci
. 2024 Jul;
137(13).
PMID: 38995113
Mechanosensing, or how cells sense and respond to the physical environment, is crucial for many aspects of biological function, ranging from cell movement during development to cancer metastasis, the immune...
4.
Dietze K, Nguyen K, Pathni A, Fazekas F, Baker J, Gebru E, et al.
bioRxiv
. 2024 Jun;
PMID: 38915559
Chimeric antigen receptor (CAR) T cell therapy has shown remarkable efficacy in cancer treatment. Still, most patients receiving CAR T cells relapse within 5 years of treatment. CAR-mediated trogocytosis (CMT)...
5.
Bhanja A, Seeley-Fallen M, Lazzaro M, Upadhyaya A, Song W
Elife
. 2023 Dec;
12.
PMID: 38085658
Antigen-induced B-cell receptor (BCR) signaling is critical for initiating and regulating B-cell activation. The actin cytoskeleton plays essential roles in BCR signaling. Upon encountering cell-surface antigens, actin-driven B-cell spreading amplifies...
6.
Wagh K, Stavreva D, Upadhyaya A, Hager G
Annu Rev Cell Dev Biol
. 2023 Aug;
39:277-305.
PMID: 37540844
Cells must tightly regulate their gene expression programs and yet rapidly respond to acute biochemical and biophysical cues within their environment. This information is transmitted to the nucleus through various...
7.
Wagh K, Stavreva D, Jensen R, Paakinaho V, Fettweis G, Schiltz R, et al.
Sci Adv
. 2023 Jun;
9(24):eade1122.
PMID: 37315128
How chromatin dynamics relate to transcriptional activity remains poorly understood. Using single-molecule tracking, coupled with machine learning, we show that histone H2B and multiple chromatin-bound transcriptional regulators display two distinct...
8.
Bhanja A, Seeley-Fallen M, Lazzaro M, Upadhyaya A, Song W
bioRxiv
. 2023 Mar;
PMID: 36993351
Antigen-induced B-cell receptor (BCR) signaling is critical for initiating and regulating B-cell activation. The actin cytoskeleton plays essential roles in BCR signaling. Upon encountering cell-surface antigens, actin-driven B-cell spreading amplifies...
9.
Johnson T, Fettweis G, Wagh K, Almeida-Prieto B, Krishnamurthy M, Upadhyaya A, et al.
bioRxiv
. 2023 Feb;
PMID: 36789429
The glucocorticoid and mineralocorticoid receptors (GR and MR, respectively) have distinct, yet overlapping physiological and pathophysiological functions. There are indications that both receptors interact functionally and physically, but the precise...
10.
Li X, Wu Y, Su Y, Rey-Suarez I, Matthaeus C, Updegrove T, et al.
Nat Biotechnol
. 2023 Jan;
41(9):1307-1319.
PMID: 36702897
The axial resolution of three-dimensional structured illumination microscopy (3D SIM) is limited to ∼300 nm. Here we present two distinct, complementary methods to improve axial resolution in 3D SIM with...