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Arpit Kumar Pradhan

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Articles 9
Citations 25
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Recent Articles
1.
Shi Q, Wang X, Pradhan A, Fenzl T, Rammes G
Int J Mol Sci . 2024 Jul; 25(13). PMID: 39000499
General anesthetics may accelerate the neuropathological changes related to Alzheimer's disease (AD), of which amyloid beta (Aβ)-induced toxicity is one of the main causes. However, the interaction of general anesthetics...
2.
Pradhan A, Rupprecht R, Rammes G
Neural Regen Res . 2024 Jul; 20(4):1090-1091. PMID: 38989945
No abstract available.
3.
Pradhan A, Neumuller T, Klug C, Fuchs S, Schlegel M, Ballmann M, et al.
Transl Psychiatry . 2023 Oct; 13(1):332. PMID: 37891168
Alzheimer's disease (AD) is characterized by the accumulation of β-amyloid peptide (Aβ). It affects cognition and leads to memory impairment. The mitochondrial translocator protein (TSPO) plays an essential role in...
4.
Rupprecht R, Pradhan A, Kufner M, Brunner L, Nothdurfter C, Wein S, et al.
Eur Arch Psychiatry Clin Neurosci . 2022 Dec; 273(7):1477-1487. PMID: 36574032
There is need for novel fast acting treatment options in affective disorders. 3α-reduced neurosteroids such as allopregnanolone are powerful positive allosteric modulators of GABA receptors and target also extrasynaptic receptors....
5.
Haresh Liya D, Anand N, Jainarayanan A, Elanchezhian M, Seetharaman M, Balakannan D, et al.
J Biomol Struct Dyn . 2022 Sep; 41(16):7931-7948. PMID: 36173706
The evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus since its emergence in 2019 has yielded several new viral variants with varied infectivity, disease severity, and antigenicity....
6.
Pradhan A, Shi Q, Tartler K, Rammes G
STAR Protoc . 2022 Sep; 3(4):101687. PMID: 36125933
Quantification of synaptic engulfment is an indirect measurement of synaptic pruning. Here, we provide a detailed protocol for the volumetric rendering of individual high-resolution astrocytes in the CA1 region of...
7.
Wang X, Shi Q, Pradhan A, Ziegon L, Schlegel M, Rammes G
Int J Mol Sci . 2022 Jun; 23(12). PMID: 35743082
Evidence indicates that inhalative anesthetics enhance the β-site amyloid precursor protein (APP)-cleaving enzyme (BACE) activity, increase amyloid beta 1-42 (Aβ) aggregation, and modulate dendritic spine dynamics. However, the mechanisms of...
8.
Prakash P, Pradhan A, Sheeba V
Dis Model Mech . 2022 Jun; 15(6). PMID: 35645202
Circadian disturbances are early features of neurodegenerative diseases, including Huntington's disease (HD). Emerging evidence suggests that circadian decline feeds into neurodegenerative symptoms, exacerbating them. Therefore, we asked whether known neurotoxic...
9.
Anand N, Haresh Liya D, Pradhan A, Tayal N, Bansal A, Donakonda S, et al.
PLoS One . 2021 Mar; 16(3):e0248553. PMID: 33735271
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is a novel human coronavirus strain (HCoV) was initially reported in December 2019 in Wuhan City, China. This acute infection caused...