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Arno Amann

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Articles 35
Citations 434
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Recent Articles
1.
Sokolova V, Gruber R, Pammer L, Kocher F, Klieser E, Amann A, et al.
Mol Biol Rep . 2024 Dec; 52(1):87. PMID: 39729162
In the last decades the survival of metastatic gastrointestinal (GI) cancer patients could have been significantly extended due to the introduction of targeted- and immunotherapy. However, only the minority of...
2.
Hamid M, Pammer L, Lentner T, Doleschal B, Gruber R, Kocher F, et al.
Curr Oncol Rep . 2024 Jul; 26(10):1258-1270. PMID: 39080202
Purpose Of Review: This review will explore various strategies to rendering MSS mCRCs susceptible to ICI. Moreover, we will provide an overview of potential biomarkers that may aid to better...
3.
Koeck S, Amann A, Kern J, Zwierzina M, Lorenz E, Sopper S, et al.
Oncoimmunology . 2023 Dec; 12(1):2274130. PMID: 38126028
Cancer associated fibroblasts (CAF) are known to orchestrate multiple components of the tumor microenvironment, whereas the influence of the whole stromal-fibroblast compartment is less understood. Here, an extended stromal fibroblast...
4.
Piringer G, Gruenberger T, Thaler J, Kuhrer I, Kaczirek K, Langle F, et al.
Front Oncol . 2023 Aug; 13:1231600. PMID: 37621684
Background: Twenty percent of colorectal cancer liver metastases (CLMs) are initially resectable with a 5-year survival rate of 25%-40%. Perioperative folinic acid, 5-fluorouracil, oxaliplatin (FOLFOX) increases progression-free survival (PFS). In...
5.
Zimmer K, Kocher F, Untergasser G, Kircher B, Amann A, Baca Y, et al.
NPJ Precis Oncol . 2023 Jul; 7(1):64. PMID: 37400502
Polybromo-1 (PBRM1) loss of function mutations are present in a fraction of biliary tract cancers (BTCs). PBRM1, a subunit of the PBAF chromatin-remodeling complex, is involved in DNA damage repair....
6.
Woll E, Amann A, Eisterer W, Gerger A, Grunberger B, Rumpold H, et al.
Anticancer Res . 2023 Jun; 43(7):2889-2897. PMID: 37351962
Over the last decade, therapeutic options for patients with gastric cancer have improved significantly. However, despite these recent advances, mortality is still substantial. Surgery and chemotherapy represent the cornerstones of...
7.
Gamerith G, Kloppenburg M, Mildner F, Amann A, Merkelbach-Bruse S, Heydt C, et al.
Cancers (Basel) . 2022 Oct; 14(20). PMID: 36291897
Effective targeted treatment strategies resulted from molecular profiling of lung cancer with distinct prevalent mutation profiles in smokers and non-smokers. Although Rn is the second most important risk factor, data...
8.
Gamerith G, Mildner F, Merkel P, Harris K, Cooney L, Lim N, et al.
Ann Rheum Dis . 2022 Aug; 82(2):253-261. PMID: 35973802
Objectives: We investigated whether soluble immune checkpoints (sICPs) predict treatment resistance, relapse and infections in patients with antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV). Methods: Plasma sICP concentrations from available samples...
9.
Seeber A, Battaglin F, Zimmer K, Kocher F, Baca Y, Xiu J, et al.
Clin Cancer Res . 2022 Mar; 28(9):1863-1870. PMID: 35254413
Purpose: Gene fusions involving R-spondin (RSPOfp) and RNF43 mutations have been shown to drive Wnt-dependent tumor initiation in colorectal cancer. Herein, we aimed to characterize the molecular features of RSPOfp/RNF43...
10.
Schlintl V, Huemer F, Rinnerthaler G, Melchardt T, Winder T, Reimann P, et al.
BMC Cancer . 2022 Jan; 22(1):51. PMID: 35012477
Background: Safety and efficacy of immune checkpoint inhibitors in advanced gastric or gastroesophageal junction (GEJ) cancer could be demonstrated in predominantly Asian cohorts, whereas data in Western patients outside of...