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Arne Soicke

Explore the profile of Arne Soicke including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 51
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Recent Articles
1.
Barone M, Muller M, Chiha S, Ren J, Albat D, Soicke A, et al.
Proc Natl Acad Sci U S A . 2020 Nov; 117(47):29684-29690. PMID: 33184177
Battling metastasis through inhibition of cell motility is considered a promising approach to support cancer therapies. In this context, Ena/VASP-depending signaling pathways, in particular interactions with their EVH1 domains, are...
2.
Reuter C, Opitz R, Soicke A, Dohmen S, Barone M, Chiha S, et al.
Chemistry . 2015 Apr; 21(23):8464-70. PMID: 25906737
With the aim of developing polyproline type II helix (PPII) secondary-structure mimetics for the modulation of prolin-rich-mediated protein-protein interactions, the novel diproline mimetic ProM-2 was designed by bridging the two...
3.
Opitz R, Muller M, Reuter C, Barone M, Soicke A, Roske Y, et al.
Proc Natl Acad Sci U S A . 2015 Apr; 112(16):5011-6. PMID: 25848013
Small-molecule competitors of protein-protein interactions are urgently needed for functional analysis of large-scale genomics and proteomics data. Particularly abundant, yet so far undruggable, targets include domains specialized in recognizing proline-rich...
4.
Velcicky J, Soicke A, Steiner R, Schmalz H
J Am Chem Soc . 2011 Apr; 133(18):6948-51. PMID: 21504197
A one-pot protocol for the cyanomethylation of aryl halides through a palladium-catalyzed reaction with isoxazole-4-boronic acid pinacol ester was developed. Mechanistically, the reaction proceeds through (1) Suzuki coupling, (2) base-induced...