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Arne Egesten

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Articles 111
Citations 1087
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Recent Articles
1.
Adler A, Bergwik J, Padra M, Papareddy P, Schmidt T, Dahlgren M, et al.
Respir Res . 2025 Mar; 26(1):101. PMID: 40087604
Background: Despite progress in the treatment of asthma, there is an unmet need for additional therapeutic strategies, not least to avoid side-effects of corticosteroids. The enzyme MutT homolog 1 (MTH1)...
2.
Blomberg A, Toren K, Liv P, Granasen G, Andersson A, Behndig A, et al.
Ann Am Thorac Soc . 2024 Aug; 21(12):1678-1687. PMID: 39133529
Chronic obstructive pulmonary disease (COPD) includes respiratory symptoms and chronic airflow limitation (CAL). In some cases, emphysema and impaired diffusing capacity of the lung for carbon monoxide (Dl) are present,...
3.
Sundler Bjorkman L, Pirouzifard M, Grover S, Egesten A, Sundquist J, Sundquist K, et al.
Blood . 2024 May; 144(4):435-444. PMID: 38767511
Hereditary angioedema (HAE), caused by C1 inhibitor protein deficiency, was recently shown to be associated with an increased risk for venous thromboembolism (VTE). To our knowledge, this is the first...
4.
Bergwik J, Liu J, Padra M, Bhongir R, Tanner L, Xiang Y, et al.
Respir Res . 2024 Mar; 25(1):146. PMID: 38555460
Background: In chronic pulmonary diseases characterized by inflammation and airway obstruction, such as asthma and COPD, there are unmet needs for improved treatment. Quinolines is a group of small heterocyclic...
5.
Bergwik J, Bhongir R, Padra M, Adler A, Olm F, Lang P, et al.
Immunology . 2024 Jan; 171(4):583-594. PMID: 38178705
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disorder involving scarring of pulmonary tissue and a subsequent decrease in respiratory capacity, ultimately resulting in death. Tartrate resistant acid phosphatase 5...
6.
Pesonen I, Johansson F, Johnsson A, Blomberg A, Boijsen M, Brandberg J, et al.
ERJ Open Res . 2023 Sep; 9(5). PMID: 37753274
Background: Interstitial lung abnormalities (ILA) are incidental findings on chest computed tomography (CT). These patterns can present at an early stage of fibrotic lung disease. Our aim was to estimate...
7.
Pan L, Vlahopoulos S, Tanner L, Bergwik J, Bacsi A, Radak Z, et al.
Front Immunol . 2023 Aug; 14:1186369. PMID: 37614238
Recent advances have uncovered the non-random distribution of 7, 8-dihydro-8-oxoguanine (8-oxoGua) induced by reactive oxygen species, which is believed to have epigenetic effects. Its cognate repair protein, 8-oxoguanine DNA glycosylase...
8.
Grover S, Sundler Bjorkman L, Egesten A, Moll S, Mackman N
J Thromb Haemost . 2023 Jan; 21(1):180-182. PMID: 36695383
No abstract available.
9.
Pan L, Hao W, Xue Y, Wang K, Zheng X, Luo J, et al.
Nucleic Acids Res . 2023 Jan; 51(3):1087-1102. PMID: 36651270
Reactive oxygen species (ROS) are implicated in epithelial cell-state transition and deposition of extracellular matrix upon airway injury. Of the many cellular targets of ROS, oxidative DNA modification is a...
10.
Tanner L, Bergwik J, Bhongir R, Puthia M, Lang P, Ali M, et al.
Front Immunol . 2022 Dec; 13:1079775. PMID: 36569898
Introduction: During airway infection, upregulation of proinflammatory cytokines and subsequent immune cell recruitment is essential to mitigate bacterial infection. Conversely, during prolonged and non-resolving airway inflammation, neutrophils contribute to tissue...