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Arne Diehl

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Articles 21
Citations 85
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Recent Articles
1.
Abdul-Aziz M, Diehl A, Liu X, Cheng V, Corley A, Gilder E, et al.
Antimicrob Agents Chemother . 2024 Dec; 69(2):e0143524. PMID: 39692515
This study aimed to describe the population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation (ECMO) and to identify dosing regimens with a high likelihood of achieving...
2.
Pai Mangalore R, Chai M, Pope J, Lee S, Padiglione A, Diehl A, et al.
BMJ Open . 2024 Jul; 14(6):e083635. PMID: 38951004
Introduction: Critically ill patients are at risk of suboptimal beta-lactam antibiotic (beta-lactam) exposure due to the impact of altered physiology on pharmacokinetics. Suboptimal concentrations can lead to treatment failure or...
3.
Diehl A, Coughlin B, Moriarty H, Joseph T, Kavnoudias H, Udy A
ASAIO J . 2024 May; 70(12):e182-e187. PMID: 38713630
Veno-arterial extracorporeal membrane oxygenation (VA ECMO) fundamentally alters patient physiology and blood flow relevant to contrast delivery for computed tomography (CT) imaging. Here, we present a comprehensive guide to contrast-enhanced...
4.
Novy E, Abdul-Aziz M, Cheng V, Burrows F, Buscher H, Corley A, et al.
Antimicrob Agents Chemother . 2023 Dec; 68(1):e0120123. PMID: 38063399
This multicenter study describes the population pharmacokinetics (PK) of fluconazole in critically ill patients receiving concomitant extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT) and includes an evaluation...
5.
Diehl A, Read A, Southwood T, Buscher H, Dennis M, Nanjayya V, et al.
Scand J Trauma Resusc Emerg Med . 2023 Dec; 31(1):89. PMID: 38044425
Background: Extracorporeal cardiopulmonary resuscitation (ECPR) is an established rescue therapy for both out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). However, there remains significant heterogeneity in populations and outcomes...
6.
Hoffman K, Diehl A, Paul E, Butt W, Burrell A
Crit Care . 2023 Oct; 27(1):384. PMID: 37789436
No abstract available.
7.
Stephens A, Seman M, Diehl A, Pilcher D, Barbaro R, Brodie D, et al.
Intensive Care Med . 2023 Aug; 49(9):1090-1099. PMID: 37548758
Purpose: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a complex and high-risk life support modality used in severe cardiorespiratory failure. ECMO survival scores are used clinically for patient prognostication and outcomes...
8.
Tatucu-Babet O, Diehl A, Kratzing C, Lambell K, Burrell A, Tierney A, et al.
Eur J Clin Nutr . 2023 May; 77(9):888-894. PMID: 37198437
Background/objectives: Traditional indirect calorimetry is unable to capture complete gas exchange in patients receiving venoarterial extracorporeal membrane oxygenation (VA ECMO). We aimed to determine the feasibility of using a modified...
9.
Hoffman K, Diehl A, Paul E, Burrell A
ASAIO J . 2023 May; 69(7):e308-e314. PMID: 37146593
Membrane oxygenator failure during venovenous (V-V) extracorporeal membrane oxygenation (ECMO) can lead to life-threatening hypoxia, high replacement costs, and may be associated with a hyperfibrinolytic state and bleeding. The current...
10.
Shekar K, Abdul-Aziz M, Cheng V, Burrows F, Buscher H, Cho Y, et al.
Am J Respir Crit Care Med . 2022 Oct; 207(6):704-720. PMID: 36215036
Data suggest that altered antimicrobial concentrations are likely during extracorporeal membrane oxygenation (ECMO). The primary aim of this analysis was to describe the pharmacokinetics (PKs) of antimicrobials in critically ill...