Arnault Graindorge
Overview
Explore the profile of Arnault Graindorge including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
404
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0
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Recent Articles
1.
Sanchez S, Pouzet E, Guimbaud L, Graindorge A, Berry L, Besteiro S
Mol Biol Cell
. 2025 Jan;
36(3):ar32.
PMID: 39878652
Glycolysis is a conserved metabolic pathway that converts glucose into pyruvate in the cytosol, producing ATP and NADH. In and several other apicomplexan parasites, some glycolytic enzymes have isoforms located...
2.
The Toxoplasma rhoptry protein ROP55 is a major virulence factor that prevents lytic host cell death
Grilo Ruivo M, Shin J, Lenz T, Matsuno S, Yanes K, Graindorge A, et al.
Nat Commun
. 2025 Jan;
16(1):709.
PMID: 39814722
Programmed-cell death is an antimicrobial defense mechanism that promotes clearance of intracellular pathogens. Toxoplasma counteracts host immune defenses by secreting effector proteins into host cells; however, how the parasite evades...
3.
Seveno M, Loubens M, Berry L, Graindorge A, Lebrun M, Lavazec C, et al.
PLoS Pathog
. 2025 Jan;
21(1):e1012455.
PMID: 39808636
A sustained blood-stage infection of the human malaria parasite P. falciparum relies on the active exit of merozoites from their host erythrocytes. During this process, named egress, the infected red...
4.
Renaud E, Maupin A, Bordat Y, Graindorge A, Berry L, Besteiro S
Virulence
. 2024 Mar;
15(1):2329566.
PMID: 38509723
is an obligate intracellular parasite responsible for a pathology called toxoplasmosis, which primarily affects immunocompromised individuals and developing foetuses. The parasite can scavenge essential nutrients from its host to support...
5.
Aquilini E, Mendonca Cova M, Mageswaran S, Dos Santos Pacheco N, Sparvoli D, Penarete-Vargas D, et al.
Nat Microbiol
. 2021 Jan;
6(4):425-434.
PMID: 33495622
Apicomplexa are unicellular eukaryotes and obligate intracellular parasites, including Plasmodium (the causative agent of malaria) and Toxoplasma (one of the most widespread zoonotic pathogens). Rhoptries, one of their specialized secretory...
6.
Berry L, Chen C, Francia M, Guerin A, Graindorge A, Saliou J, et al.
Cell Mol Life Sci
. 2018 Jul;
75(23):4417-4443.
PMID: 30051161
The phylum Apicomplexa encompasses deadly pathogens such as malaria and Cryptosporidium. Apicomplexa cell division is mechanistically divergent from that of their mammalian host, potentially representing an attractive source of drug...
7.
Bodilis J, Denet E, Brothier E, Graindorge A, Favre-Bonte S, Nazaret S
Front Microbiol
. 2018 Mar;
9:383.
PMID: 29559964
The epidemic ET12 lineage belongs to the genomovar IIIA including the reference strain J2315, a highly transmissible epidemic lineage. Members of this lineage are able to cause lung infections in...
8.
Mueller C, Graindorge A, Soldati-Favre D
Curr Opin Microbiol
. 2017 Nov;
40:113-122.
PMID: 29161623
Myosin motors are one of the largest protein families in eukaryotes that exhibit divergent cellular functions. Their roles in protozoans, a diverse group of anciently diverged, single celled organisms with...
9.
Frenal K, Jacot D, Hammoudi P, Graindorge A, Maco B, Soldati-Favre D
Nat Commun
. 2017 Jun;
8:15710.
PMID: 28593938
The obligate intracellular parasite Toxoplasma gondii possesses a repertoire of 11 myosins. Three class XIV motors participate in motility, invasion and egress, whereas the class XXII myosin F is implicated...
10.
Jacot D, Tosetti N, Pires I, Stock J, Graindorge A, Hung Y, et al.
Cell Host Microbe
. 2016 Dec;
20(6):731-743.
PMID: 27978434
Apicomplexa exhibit a unique form of substrate-dependent gliding motility central for host cell invasion and parasite dissemination. Gliding is powered by rearward translocation of apically secreted transmembrane adhesins via their...