Arig Ibrahim-Hashim
Overview
Explore the profile of Arig Ibrahim-Hashim including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
1772
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Recent Articles
1.
Walling L, Gamache M, Gonzalez-Pech R, Harwood V, Ibrahim-Hashim A, Jung J, et al.
Sci Total Environ
. 2025 Mar;
970:178826.
PMID: 40054249
Conservation genomics is a rapidly growing subdiscipline of conservation biology that uses genome-wide information to inform management of biodiversity at all levels. Such efforts typically focus on species or systems...
2.
Bhattacharya R, Brown J, Gatenby R, Ibrahim-Hashim A
Semin Cancer Biol
. 2024 Jul;
102-103:17-24.
PMID: 38969311
Oxygen played a pivotal role in the evolution of multicellularity during the Cambrian Explosion. Not surprisingly, responses to fluctuating oxygen concentrations are integral to the evolution of cancer-a disease characterized...
3.
Jardim-Perassi B, Irrera P, Oluwatola O, Abrahams D, Estrella V, Ordway B, et al.
Biomedicines
. 2024 Feb;
12(2).
PMID: 38398062
Acidosis is an important immunosuppressive mechanism that leads to tumor growth. Therefore, we investigated the neutralization of tumor acidity to improve immunotherapy response. L-DOS47, a new targeted urease immunoconjugate designed...
4.
Dighe A, Maziarz J, Ibrahim-Hashim A, Gatenby R, Kshitiz , Levchenko A, et al.
iScience
. 2024 Jan;
27(1):108593.
PMID: 38174318
Gene expression change is a dominant mode of evolution. Mutations, however, can affect gene expression in multiple cell types. Therefore, gene expression evolution in one cell type can lead to...
5.
Abrahams D, Ibrahim-Hashim A, Ackerman R, Brown J, Whelan C, Garfinkel M, et al.
PLoS One
. 2023 Oct;
18(10):e0292492.
PMID: 37816047
Introduction: Volatile and intravenous anesthetics may worsen oncologic outcomes in basic science animal models. These effects may be related to suppressed innate and adaptive immunity, decreased immunosurveillance, and disrupted cellular...
6.
Jardim-Perassi B, Irrera P, Abrahams D, Estrella V, Ordway B, Byrne S, et al.
bioRxiv
. 2023 Sep;
PMID: 37693389
Acidosis is an important immunosuppressive mechanism that leads to tumor growth. Therefore, we investigated the neutralization of tumor acidity to improve immunotherapy response. L-DOS47, a new targeted urease immunoconjugate designed...
7.
Jardim-Perassi B, Irrera P, Lau J, Budzevich M, Whelan C, Abrahams D, et al.
Contrast Media Mol Imaging
. 2023 Jan;
2023():1944970.
PMID: 36704211
The extracellular pH (pHe) of solid tumors is often acidic, as a consequence of the Warburg effect, and an altered metabolic state is often associated with malignancy. It has been...
8.
Gillies R, Ibrahim-Hashim A, Ordway B, Gatenby R
Front Oncol
. 2022 Dec;
12:981718.
PMID: 36452492
Clinical Trial Registration: clinicaltrials.gov, identifier NCT01350583, NCT01198821 and NCT01846429.
9.
Rentzeperis F, Miller N, Ibrahim-Hashim A, Gillies R, Gatenby R, Wallace D
Math Biosci
. 2022 Sep;
352:108909.
PMID: 36108797
Clinical cancers are typically spatially and temporally heterogeneous, containing multiple microenvironmental habitats and diverse phenotypes and/or genotypes, which can interact through resource competition and direct or indirect interference. A common...
10.
Freischel A, Damaghi M, Cunningham J, Ibrahim-Hashim A, Gillies R, Gatenby R, et al.
Sci Rep
. 2021 Mar;
11(1):4908.
PMID: 33649456
Tumors are highly dynamic ecosystems in which diverse cancer cell subpopulations compete for space and resources. These complex, often non-linear interactions govern continuous spatial and temporal changes in the size...