Arianna De Rosa
Overview
Explore the profile of Arianna De Rosa including associated specialties, affiliations and a list of published articles.
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13
Citations
145
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Recent Articles
1.
Di Maio A, Nuzzo T, Gilio L, Serra M, Buttari F, Errico F, et al.
Neurobiol Dis
. 2023 Jun;
184:106203.
PMID: 37336364
L-serine generated in astrocytes plays a pivotal role in modulating essential neurometabolic processes, while its enantiomer, D-serine, specifically regulates NMDA receptor (NMDAR) signalling. Despite their physiological relevance in modulating cerebral...
2.
Lombardo B, Pagani M, De Rosa A, Nunziato M, Migliarini S, Garofalo M, et al.
Transl Psychiatry
. 2022 Aug;
12(1):305.
PMID: 35915065
The D-aspartate oxidase (DDO) gene encodes the enzyme responsible for the catabolism of D-aspartate, an atypical amino acid enriched in the mammalian brain and acting as an endogenous NMDA receptor...
3.
De Rosa A, Fontana A, Nuzzo T, Garofalo M, Di Maio A, Punzo D, et al.
Schizophrenia (Heidelb)
. 2022 Feb;
8(1):8.
PMID: 35217646
Schizophrenia is a disorder of synaptic plasticity and aberrant connectivity in which a major dysfunction in glutamate synapse has been suggested. However, a multi-level approach tackling diverse clusters of interacting...
4.
De Rosa A, Di Maio A, Torretta S, Garofalo M, Giorgelli V, Masellis R, et al.
Biomolecules
. 2022 Feb;
12(2).
PMID: 35204828
Schizophrenia (SCZ) is a polygenic severe mental illness. Genome-wide association studies (GWAS) have detected genomic variants associated with this psychiatric disorder and pathway analyses have indicated immune system and dopamine...
5.
Di Maio A, De Rosa A, Pelucchi S, Garofalo M, Marciano B, Nuzzo T, et al.
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163460
Schizophrenia (SCZ) is a mental illness characterized by aberrant synaptic plasticity and connectivity. A large bulk of evidence suggests genetic and functional links between postsynaptic abnormalities and SCZ. Here, we...
6.
Stampanoni Bassi M, Nuzzo T, Gilio L, Miroballo M, Casamassa A, Buttari F, et al.
J Neurochem
. 2021 Sep;
159(5):857-866.
PMID: 34547109
Excessive extracellular concentrations of L-glutamate (L-Glu) can be neurotoxic and contribute to neurodegenerative processes in multiple sclerosis (MS). The association between cerebrospinal fluid (CSF) L-Glu levels, clinical features, and inflammatory...
7.
Grimaldi M, Marino C, Buonocore M, Santoro A, Sommella E, Merciai F, et al.
J Proteome Res
. 2020 Dec;
20(1):727-739.
PMID: 33274941
d-Amino acids were believed to occur only in bacteria and invertebrates. Today, it is well known that d-amino acids are also present in mammalian tissues in a considerable amount. In...
8.
Usiello A, Di Fiore M, De Rosa A, Falvo S, Errico F, Santillo A, et al.
Int J Mol Sci
. 2020 Nov;
21(22).
PMID: 33218144
The endogenous amino acids serine and aspartate occur at high concentrations in free D-form in mammalian organs, including the central nervous system and endocrine glands. D-serine (D-Ser) is largely localized...
9.
Calabrese V, Di Maio A, Marino G, Cardinale A, Natale G, De Rosa A, et al.
Front Aging Neurosci
. 2020 Aug;
12:230.
PMID: 32848709
Levodopa (L-DOPA) treatment is the main gold-standard therapy for Parkinson disease (PD). Besides good antiparkinsonian effects, prolonged use of this drug is associated to the development of involuntary movements known...
10.
Eshraghi M, Ramirez-Jarquin U, Shahani N, Nuzzo T, De Rosa A, Swarnkar S, et al.
Sci Adv
. 2020 May;
6(18):eaaz7001.
PMID: 32426479
The therapeutic effects of l-3,4-dihydroxyphenylalanine (l-DOPA) in patients with Parkinson's disease (PD) severely diminishes with the onset of abnormal involuntary movement, l-DOPA-induced dyskinesia (LID). However, the molecular mechanisms that promote...