Archana Vijayakumar
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Explore the profile of Archana Vijayakumar including associated specialties, affiliations and a list of published articles.
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21
Citations
1078
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Recent Articles
11.
Vijayakumar A, Buffin N, Gallagher E, Blank J, Wu Y, Yakar S, et al.
Endocrinology
. 2013 Jul;
154(10):3776-83.
PMID: 23861377
In this study, we investigated whether loss of GH receptor (GHR) signaling in postnatal skeletal muscle alters muscle mass and regenerative ability in adult mice and whether this was dependent...
12.
Vijayakumar A, Wu Y, Buffin N, Li X, Sun H, Gordon R, et al.
PLoS One
. 2012 Oct;
7(9):e44777.
PMID: 23024761
Background: Growth hormone (GH) stimulates whole-body lipid oxidation, but its regulation of muscle lipid oxidation is not clearly defined. Mice with a skeletal muscle-specific knockout of the GH receptor (mGHRKO...
13.
Vijayakumar A, Yakar S, LeRoith D
Front Endocrinol (Lausanne)
. 2012 Jun;
2:32.
PMID: 22654802
Growth hormone (GH), a master regulator of somatic growth, also regulates carbohydrate and lipid metabolism via complex interactions with insulin and insulin-like growth factor-1 (IGF-1). Data from human and rodent...
14.
Vijayakumar A, Wu Y, Sun H, Li X, Jeddy Z, Liu C, et al.
Diabetes
. 2011 Dec;
61(1):94-103.
PMID: 22187377
Growth hormone (GH) exerts diverse tissue-specific metabolic effects that are not revealed by global alteration of GH action. To study the direct metabolic effects of GH in the muscle, we...
15.
Wu Y, Liu C, Sun H, Vijayakumar A, Giglou P, Qiao R, et al.
J Clin Invest
. 2011 May;
121(6):2422-6.
PMID: 21555853
Insulin, growth hormone (GH), and insulin-like growth factor-1 (IGF-1) play key roles in the regulation of β cell growth and function. Although β cells express the GH receptor, the direct...
16.
Cannata D, Vijayakumar A, Fierz Y, LeRoith D
Adv Pediatr
. 2010 Nov;
57(1):331-51.
PMID: 21056746
No abstract available.
17.
Fierz Y, Novosyadlyy R, Vijayakumar A, Yakar S, LeRoith D
Endocr Relat Cancer
. 2010 Aug;
17(4):941-51.
PMID: 20801951
Type 2 diabetes increases breast cancer risk and mortality, and hyperinsulinemia is a major mediator of this effect. The mammalian target of rapamycin (mTOR) is activated by insulin and is...
18.
Cannata D, Fierz Y, Vijayakumar A, LeRoith D
Mt Sinai J Med
. 2010 Mar;
77(2):197-213.
PMID: 20309918
Epidemiological studies have demonstrated an association between type 2 diabetes and cancer. Type 2 diabetes is characterized by insulin resistance and hyperinsulinemia. Hyperinsulinemia may lead to cancer through insulin's effect...
19.
Novosyadlyy R, Lann D, Vijayakumar A, Rowzee A, Lazzarino D, Fierz Y, et al.
Cancer Res
. 2010 Jan;
70(2):741-51.
PMID: 20068149
Epidemiologic studies suggest that type 2 diabetes (T2D) increases breast cancer risk and mortality, but there is limited experimental evidence supporting this association. Moreover, there has not been any definition...
20.
Fierz Y, Novosyadlyy R, Vijayakumar A, Yakar S, LeRoith D
Diabetes
. 2009 Dec;
59(3):686-93.
PMID: 19959755
Objective: Type 2 diabetes increases breast cancer risk and mortality, and hyperinsulinemia has been identified as a major factor linking these two diseases. Thus, we hypothesized that pharmacological reduction of...