Aparna Natarajan
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Explore the profile of Aparna Natarajan including associated specialties, affiliations and a list of published articles.
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15
Citations
233
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0
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Recent Articles
1.
Talsania K, Shen T, Chen X, Jaeger E, Li Z, Chen Z, et al.
Genome Biol
. 2022 Dec;
23(1):255.
PMID: 36514120
Background: The cancer genome is commonly altered with thousands of structural rearrangements including insertions, deletions, translocation, inversions, duplications, and copy number variations. Thus, structural variant (SV) characterization plays a paramount...
2.
Gopinath P, Natarajan A, Sathyanarayanan A, Veluswami S, Gopisetty G
Gene
. 2022 Jan;
815:146137.
PMID: 35007686
The extracellular matrix (ECM) is composed of a mesh of proteins, proteoglycans, growth factors, and other secretory components. It constitutes the tumor microenvironment along with the endothelial cells, cancer-associated fibroblasts,...
3.
Xiao W, Ren L, Chen Z, Fang L, Zhao Y, Lack J, et al.
Nat Biotechnol
. 2021 Sep;
39(9):1141-1150.
PMID: 34504346
Clinical applications of precision oncology require accurate tests that can distinguish true cancer-specific mutations from errors introduced at each step of next-generation sequencing (NGS). To date, no bulk sequencing study...
4.
Natarajan A, Mehra N, Rajkumar T
Med Oncol
. 2020 Oct;
37(11):101.
PMID: 33057841
Financial constraints faced by the families play a vital role in cancer treatment refusal, non-adherence, and failure of the prescribed therapy. This review aims to give an insight into the...
5.
Natarajan A, Ramachandran B, Gopisetty G, Jayavelu S, Sundersingh S, Rajkumar T
Naunyn Schmiedebergs Arch Pharmacol
. 2020 Oct;
394(2):361-371.
PMID: 33015747
Osteosarcoma has been reported with treatment failure in up to 40% of cases. Our laboratory had identified genes involved in the PPARγ pathway to be associated with doxorubicin (DOX) resistance....
6.
Natarajan A, Thangarajan R, Kesavan S
Asian Pac J Cancer Prev
. 2019 Nov;
20(11):3399-3406.
PMID: 31759365
Background: Targeted therapy in the form of highly selective tyrosine kinase inhibitors (TKIs) has transformed the treatment of chronic myeloid leukemia (CML). However, mutations in the kinase domain contribute to...
7.
Martinez-Viaud K, Lawley C, Vergara M, Ben-Zvi G, Biniashvili T, Baruch K, et al.
Gigascience
. 2019 Jan;
8(3).
PMID: 30698692
High-quality genomes are essential to resolve challenges in breeding, comparative biology, medicine, and conservation planning. New library preparation techniques along with better assembly algorithms result in continued improvements in assemblies...
8.
Natarajan A, Kumarasamy S
J Med Syst
. 2019 Jan;
43(2):25.
PMID: 30604101
Nowadays, automatic tumor detection from brain images is extremely significant for many diagnostic as well as therapeutic purposes, due to the unpredictable shape and appearance of tumors. In medical image...
9.
Natarajan A, Shah P, Mirrakhimov A, Hussain N
BMJ Case Rep
. 2013 May;
2013.
PMID: 23645642
A 29-year-old Caucasian man presented for the evaluation of a new onset of shortness of breath associated with cough and wheeze for 1 day. The history was significant for a...
10.
Hussain N, Khan M, Natarajan A, Mohammedabdul M, Mustafa U, Yedulla K, et al.
Case Rep Oncol Med
. 2013 Mar;
2013:420565.
PMID: 23533873
Hypercalcemia is a common medical problem with an estimated prevalence of 15% among hospitalized patients. Multiple myeloma (MM) and primary hyperparathyroidism (PHPT) are among the most common causes of hypercalcemia...