Anurag Kumar Sinha
Overview
Explore the profile of Anurag Kumar Sinha including associated specialties, affiliations and a list of published articles.
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10
Citations
112
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Recent Articles
1.
Kabir A, Mukilarasi B, Manohar A, Gadani M, Sinha A, Sharma P, et al.
Int J Biol Macromol
. 2025 Feb;
303:140483.
PMID: 39904451
The space microgravity environment and cosmic radiation pose a significant threat to musculoskeletal health, particularly bone mass. However, the critical mechanism underlying space-induced bone loss and its relation to cellular...
2.
Sinha A, Laursen M, Rask Licht T
Trends Microbiol
. 2024 Aug;
PMID: 39095208
During the past two decades, gut microbiome studies have established the significant impact of the gut microbiota and its metabolites on host health. However, the molecular mechanisms governing the production...
3.
Sinha A, Winther K
Commun Biol
. 2021 Apr;
4(1):434.
PMID: 33790389
Bacteria synthesize guanosine tetra- and penta phosphate (commonly referred to as (p)ppGpp) in response to environmental stresses. (p)ppGpp reprograms cell physiology and is essential for stress survival, virulence and antibiotic...
4.
Sinha A, Lobner-Olesen A, Riber L
Front Microbiol
. 2020 Sep;
11:582113.
PMID: 32983079
The stringent response regulates bacterial growth rate and is important for cell survival under changing environmental conditions. The effect of the stringent response is pleiotropic, affecting almost all biological processes...
5.
Sinha A, Possoz C, Leach D
FEMS Microbiol Rev
. 2020 Apr;
44(3):351-368.
PMID: 32286623
It is well established that DNA double-strand break (DSB) repair is required to underpin chromosomal DNA replication. Because DNA replication forks are prone to breakage, faithful DSB repair and correct...
6.
Sondberg E, Sinha A, Gerdes K, Semsey S
Front Microbiol
. 2019 Sep;
10:2053.
PMID: 31543875
Horizontal gene transfer through natural competence is an important driving force of bacterial evolution and antibiotic resistance development. In several Gram-negative pathogens natural competence is regulated by the concerted action...
7.
Sinha A, Winther K, Roghanian M, Gerdes K
Mol Microbiol
. 2019 Aug;
112(4):1339-1349.
PMID: 31400173
Bacteria undergoing nutrient starvation induce the ubiquitous stringent response, resulting in gross physiological changes that reprograms cell metabolism from fast to slow growth. The stringent response is mediated by the...
8.
Sinha A, Possoz C, Durand A, Desfontaines J, Barre F, Leach D, et al.
PLoS Genet
. 2018 Mar;
14(3):e1007256.
PMID: 29522563
It was recently reported that the recBC mutants of Escherichia coli, deficient for DNA double-strand break (DSB) repair, have a decreased copy number of their terminus region. We previously showed...
9.
Sinha A, Durand A, Desfontaines J, Iurchenko I, Auger H, Leach D, et al.
PLoS Genet
. 2017 Oct;
13(10):e1006895.
PMID: 28968392
Marker frequency analysis of the Escherichia coli recB mutant chromosome has revealed a deficit of DNA in a specific zone of the terminus, centred on the dif/TerC region. Using fluorescence...
10.
Michel B, Sinha A
Mol Microbiol
. 2017 Mar;
104(6):1008-1026.
PMID: 28342235
The Escherichia coli holD mutant is poorly viable because the stability of holoenzyme polymerase III (Pol III HE) on DNA is compromised. Consequently, the SOS response is induced and the...