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Anuradha Doddaballapur

Explore the profile of Anuradha Doddaballapur including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 760
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Recent Articles
1.
Phowira J, Bakhashab S, Doddaballapur A, Weaver J
Front Endocrinol (Lausanne) . 2022 Aug; 13:894093. PMID: 35923624
Background: Subclinical thyrotoxicosis (SCT) is defined by low or undetectable thyroid-stimulating hormones and normal thyroid hormones. The treatment of SCT is uncertain despite being associated with increased cardiovascular risk (CVR)...
2.
Andrade J, Shi C, Costa A, Choi J, Kim J, Doddaballapur A, et al.
Nat Cell Biol . 2021 Apr; 23(4):413-423. PMID: 33795871
Endothelial cells (ECs) adapt their metabolism to enable the growth of new blood vessels, but little is known how ECs regulate metabolism to adopt a quiescent state. Here, we show...
3.
Demolli S, Doddaballapur A, Devraj K, Stark K, Manavski Y, Eckart A, et al.
Cardiovasc Res . 2017 Apr; 113(6):681-691. PMID: 28453731
Aims: Vessel maturation involves the recruitment of mural cells such as pericytes and smooth muscle cells. Laminar shear stress is a major trigger for vessel maturation, but the molecular mechanisms...
4.
Boeckel J, Derlet A, Glaser S, Luczak A, Lucas T, Heumuller A, et al.
Arterioscler Thromb Vasc Biol . 2016 May; 36(7):1425-33. PMID: 27199445
Objective: Jumonji C (JmjC) domain-containing proteins modify histone and nonhistone proteins thereby controlling cellular functions. However, the role of JmjC proteins in angiogenesis is largely unknown. Here, we characterize the...
5.
Fontijn R, Volger O, van der Pouw-Kraan T, Doddaballapur A, Leyen T, Baggen J, et al.
PLoS One . 2015 Dec; 10(12):e0145777. PMID: 26717516
The flow-responsive transcription factor Krüppel-like factor 2 (KLF2) maintains an anti-coagulant, anti-inflammatory endothelium with sufficient nitric oxide (NO)-bioavailability. In this study, we aimed to explore, both in vitro and in...
6.
Demolli S, Doebele C, Doddaballapur A, Lang V, Fisslthaler B, Chavakis E, et al.
J Mol Cell Cardiol . 2015 Oct; 88:111-9. PMID: 26456066
MicroRNAs are endogenously expressed small noncoding RNAs that regulate gene expression. Laminar blood flow induces atheroprotective gene expression in endothelial cells (ECs) in part by upregulating the transcription factor KLF2....
7.
Doddaballapur A, Michalik K, Manavski Y, Lucas T, Houtkooper R, You X, et al.
Arterioscler Thromb Vasc Biol . 2014 Nov; 35(1):137-45. PMID: 25359860
Objective: Cellular metabolism was recently shown to regulate endothelial cell phenotype profoundly. Whether the atheroprotective biomechanical stimulus elicited by laminar shear stress modulates endothelial cell metabolism is not known. Approach...
8.
Michalik K, You X, Manavski Y, Doddaballapur A, Zornig M, Braun T, et al.
Circ Res . 2014 Mar; 114(9):1389-97. PMID: 24602777
Rationale: The human genome harbors a large number of sequences encoding for RNAs that are not translated but control cellular functions by distinct mechanisms. The expression and function of the...