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Anuradha Balasubramanian

Explore the profile of Anuradha Balasubramanian including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 469
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Recent Articles
1.
Nagaraja T, Chen L, Balasubramanian A, Groopman J, Ghoshal K, Jacob S, et al.
PLoS One . 2023 Aug; 18(8):e0290786. PMID: 37616203
[This corrects the article DOI: 10.1371/journal.pone.0046526.].
2.
Abrams R, Yasgar A, Teramoto T, Lee M, Dorjsuren D, Eastman R, et al.
Proc Natl Acad Sci U S A . 2020 Nov; 117(49):31365-31375. PMID: 33229545
When Zika virus emerged as a public health emergency there were no drugs or vaccines approved for its prevention or treatment. We used a high-throughput screen for Zika virus protease...
3.
Balasubramanian A, Markovski M, Hoskins J, Doyle S, Wickner S
Proc Natl Acad Sci U S A . 2019 Jun; 116(25):12285-12294. PMID: 31160467
Heat shock protein 90 (Hsp90) is a highly conserved molecular chaperone involved in ATP-dependent client protein remodeling and activation. It also functions as a protein holdase, binding and stabilizing clients...
4.
Sompuram S, Vani K, Schaedle A, Balasubramanian A, Bogen S
J Histochem Cytochem . 2019 Jan; 67(4):275-289. PMID: 30628843
Positive immunohistochemistry (IHC) controls are intended to detect problems in both immunostaining and heat-induced epitope retrieval (HIER). However, it is not known what features in a control are important for...
5.
Balasubramanian A, Pilankatta R, Teramoto T, Sajith A, Nwulia E, Kulkarni A, et al.
Antiviral Res . 2018 Dec; 162:71-78. PMID: 30529358
The dengue virus is considered to be a globally important human pathogen prevalent in tropical and subtropical regions of the world. According to a recent estimate, the disease burden due...
6.
Sompuram S, Vani K, Schaedle A, Balasubramanian A, Bogen S
Arch Pathol Lab Med . 2018 Mar; 142(7):851-862. PMID: 29595317
Context: - Numerous studies highlight interlaboratory performance variability in diagnostic immunohistochemistry (IHC) testing. Despite substantial improvements over the years, the inability to quantitatively and objectively assess immunostain sensitivity complicates interlaboratory...
7.
Vani K, Sompuram S, Schaedle A, Balasubramanian A, Pilichowska M, Naber S, et al.
J Histochem Cytochem . 2017 Jul; 65(8):463-477. PMID: 28665229
Clinical Immunohistochemistry (IHC) laboratories face unique challenges in performing accurate and reproducible immunostains. Among these challenges is the use of homemade controls derived from pathological discard samples. Such positive controls...
8.
Vani K, Sompuram S, Schaedle A, Balasubramanian A, Bogen S
J Histochem Cytochem . 2017 Apr; 65(5):273-283. PMID: 28438091
An important limitation in the field of immunohistochemistry (IHC) is the inability to correlate stain intensity with specific analyte concentrations. Clinical immunohistochemical tests are not described in terms of analytic...
9.
Teramoto T, Balasubramanian A, Choi K, Padmanabhan R
J Biol Chem . 2017 Apr; 292(23):9465-9479. PMID: 28396347
Four serotypes of mosquito-borne dengue virus (DENV), evolved from a common ancestor, are human pathogens of global significance for which there is no vaccine or antiviral drug available. The N-terminal...
10.
Balasubramanian A, Teramoto T, Kulkarni A, Bhattacharjee A, Padmanabhan R
Antiviral Res . 2016 Nov; 137:141-150. PMID: 27889529
In a previous study, twelve antimalarial compounds, amodiaquine (AQ) and derivatives, were shown to have potent anti-dengue viral (DENV) activity by using the stable DENV2 Renilla luciferase reporter replicon expressing...