Anupma Nayak
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Explore the profile of Anupma Nayak including associated specialties, affiliations and a list of published articles.
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58
Citations
648
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Recent Articles
1.
Demarest K, Anantharajah A, Maxwell K, Rohanizadegan M, Bradbury A, Nathanson K, et al.
JAMA Netw Open
. 2025 Feb;
8(2):e2460312.
PMID: 39964682
Importance: Metaplastic breast cancer (MpBC) is a rare, heterogeneous disease often associated with inferior outcomes. A growing body of literature describes the clinical and molecular features of MpBC, yet limited...
2.
Clinicopathologic Features of Breast Tumors in Germline TP53 Variant-Associated Li-Fraumeni Syndrome
Narasimhamurthy M, Le A, Boruah N, Moses R, Kelly G, Bleiweiss I, et al.
Am J Surg Pathol
. 2024 Dec;
49(3):195-205.
PMID: 39629784
We present one of the largest cohorts of TP53 -pathogenic germline variants (PGVs) associated with patients with Li-Fraumeni syndrome (n = 82) with breast tumors (19 to 76 y; median...
3.
Young A, Pantel A, Kiani M, Doot R, Bagheri S, Pryma D, et al.
J Nucl Med
. 2024 Oct;
65(12):1862-1868.
PMID: 39477499
The poly(adenosine diphosphate-ribose) polymerase inhibitors (PARPi) have demonstrated efficacy in ovarian, breast, and prostate cancers, but current biomarkers do not consistently predict clinical benefit. F-fluorthanatrace (F-FTT) is an analog to...
4.
Tchou J, Gottipati S, Goldbach M, Baxter M, Venters S, Balassanian R, et al.
Ann Surg Oncol
. 2024 Aug;
31(12):8093-8101.
PMID: 39117925
Background: Rates of pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) for breast cancer have improved, especially among human epidermal growth factor 2-positive (HER2+) and triple-negative subtypes. The frequency and...
5.
Li X, Nguyen T, Zhang J, Nayak A, Liu Y, Duckworth L, et al.
Am J Surg Pathol
. 2024 Jun;
48(9):1146-1153.
PMID: 38934254
The World Health Organization (WHO) diagnostic criteria for malignant phyllodes tumor (MPT) may miss a significant number of MPTs with metastatic potential. New refined diagnostic criteria (Refined Criteria) for MPT...
6.
Boruah N, Hoyos D, Moses R, Hausler R, Desai H, Le A, et al.
bioRxiv
. 2024 Apr;
PMID: 38617260
Pathogenic germline alterations cause Li-Fraumeni Syndrome (LFS), and breast cancer is the most common cancer in LFS females. We performed first of its kind multimodal analysis of LFS breast cancer...
7.
Ito K, Harada I, Martinez C, Sato K, Lee E, Port E, et al.
Cancer Res Commun
. 2024 Mar;
4(3):946-957.
PMID: 38457262
Significance: EMT is a process directly linked to drug resistance and metastasis of cancer cells. We identified MARCH2 as a novel regulator of SNAIL, a key EMT driver, that promotes...
8.
Wineland D, Le A, Hausler R, Kelly G, Barrett E, Desai H, et al.
JCO Precis Oncol
. 2023 Aug;
7:e2300036.
PMID: 37535879
Purpose: Breast and ovarian tumors in germline carriers undergo allele-specific loss of heterozygosity, resulting in homologous recombination deficiency (HRD) and sensitivity to poly-ADP-ribose polymerase (PARP) inhibitors. This study investigated whether...
9.
Thacker G, Henry S, Nandi A, Debnath R, Singh S, Nayak A, et al.
Sci Transl Med
. 2023 Mar;
15(686):eabl4414.
PMID: 36888695
Natural killer (NK) cells are cytotoxic lymphocytes that accumulate within the tumor microenvironment and are generally considered to be antitumorigenic. Using single-cell RNA sequencing and functional analysis of multiple triple-negative...
10.
Khoury T, Rosa M, Nayak A, Karabakhtsian R, Fadare O, Li Z, et al.
Mod Pathol
. 2023 Feb;
36(2):100006.
PMID: 36853781
Adenoid cystic carcinoma (AdCC) is an uncommon type of invasive breast carcinoma with a favorable prognosis. However, some cases are aggressive. The study aims to define the clinicopathologic predictors of...