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Antonio J Santinha

Explore the profile of Antonio J Santinha including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 148
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Recent Articles
1.
Abe P, Lavalley A, Morassut I, Santinha A, Roig-Puiggros S, Javed A, et al.
Nature . 2024 Sep; 634(8034):644-651. PMID: 39261725
Layer 5 extratelencephalic (ET) neurons are present across neocortical areas and send axons to multiple subcortical targets. Two cardinal subtypes exist: (1) Slco2a1-expressing neurons (ET), which predominate in the motor...
2.
Santinha A, Klingler E, Kuhn M, Farouni R, Lagler S, Kalamakis G, et al.
Nature . 2023 Sep; 622(7982):367-375. PMID: 37730998
The ever-growing compendium of genetic variants associated with human pathologies demands new methods to study genotype-phenotype relationships in complex tissues in a high-throughput manner. Here we introduce adeno-associated virus (AAV)-mediated...
3.
Tomasello U, Klingler E, Niquille M, Mule N, Santinha A, de Vevey L, et al.
Cell Rep . 2022 Feb; 38(7):110381. PMID: 35172154
Cortical expansion in primate brains relies on enlargement of germinal zones during a prolonged developmental period. Although most mammals have two cortical germinal zones, the ventricular zone (VZ) and subventricular...
4.
Campa C, Weisbach N, Santinha A, Incarnato D, Platt R
Nat Methods . 2019 Aug; 16(9):887-893. PMID: 31406383
The ability to modify multiple genetic elements simultaneously would help to elucidate and control the gene interactions and networks underlying complex cellular functions. However, current genome engineering technologies are limited...