Antonio Espuela-Ortiz
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Explore the profile of Antonio Espuela-Ortiz including associated specialties, affiliations and a list of published articles.
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12
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96
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Recent Articles
1.
Budu-Aggrey A, Kilanowski A, Sobczyk M, Shringarpure S, Mitchell R, Reis K, et al.
Nat Commun
. 2023 Oct;
14(1):6172.
PMID: 37794016
Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS...
2.
Espuela-Ortiz A, Martin-Gonzalez E, Poza-Guedes P, Gonzalez-Perez R, Herrera-Luis E
Genes (Basel)
. 2023 Sep;
14(9).
PMID: 37761964
The astounding number of genetic variants revealed in the 15 years of genome-wide association studies of asthma has not kept pace with the goals of translational genomics. Moving asthma diagnosis...
3.
Perez-Garcia J, Espuela-Ortiz A, Hernandez-Perez J, Gonzalez-Perez R, Poza-Guedes P, Martin-Gonzalez E, et al.
J Allergy Clin Immunol
. 2023 Jun;
152(3):799-806.e6.
PMID: 37301411
Background: The upper-airway microbiome is involved in asthma exacerbations despite inhaled corticosteroid (ICS) treatment. Although human genetics regulates microbiome composition, its influence on asthma-related airway bacteria remains unknown. Objective: We...
4.
Perez-Garcia J, Gonzalez-Carracedo M, Espuela-Ortiz A, Hernandez-Perez J, Gonzalez-Perez R, Sardon-Prado O, et al.
J Allergy Clin Immunol
. 2022 Nov;
151(3):706-715.
PMID: 36343772
Background: The response to inhaled corticosteroids (ICS) in asthma is affected by the interplay of several factors. Among these, the role of the upper-airway microbiome has been scarcely investigated. We...
5.
Slob E, Faiz A, van Nijnatten J, Vijverberg S, Longo C, Kutlu M, et al.
Clin Transl Allergy
. 2022 Aug;
12(8):e12173.
PMID: 36036237
No abstract available.
6.
Herrera-Luis E, Ortega V, Ampleford E, Sio Y, Granell R, de Roos E, et al.
Pediatr Allergy Immunol
. 2022 Jun;
33(6):e13802.
PMID: 35754128
Background: Asthma exacerbations are a serious public health concern due to high healthcare resource utilization, work/school productivity loss, impact on quality of life, and risk of mortality. The genetic basis...
7.
Espuela-Ortiz A, Herrera-Luis E, Lorenzo-Diaz F, Hu D, Eng C, Villar J, et al.
J Pers Med
. 2021 Nov;
11(11).
PMID: 34834492
Asthma is a respiratory disease whose prevalence changes throughout the lifespan and differs by sex, being more prevalent in males during childhood and in females after puberty. In this study,...
8.
Maroteau C, Espuela-Ortiz A, Herrera-Luis E, Srinivasan S, Carr F, Tavendale R, et al.
PLoS One
. 2021 Sep;
16(9):e0257396.
PMID: 34550981
Leukotrienes play a central pathophysiological role in both paediatric and adult asthma. However, 35% to 78% of asthmatics do not respond to leukotriene inhibitors. In this study we tested the...
9.
Perez-Garcia J, Hernandez-Perez J, Gonzalez-Perez R, Sardon O, Martin-Gonzalez E, Espuela-Ortiz A, et al.
J Pers Med
. 2020 Sep;
10(3).
PMID: 32933076
Asthma exacerbations are a major contributor to the global disease burden, but no significant predictive biomarkers are known. The Genomics and Metagenomics of Asthma Severity (GEMAS) study aims to assess...
10.
Herrera-Luis E, Espuela-Ortiz A, Lorenzo-Diaz F, Keys K, Mak A, Eng C, et al.
Pediatr Allergy Immunol
. 2020 Aug;
32(1):106-115.
PMID: 32841424
Background: Severe asthma exacerbations are a major cause of asthma morbidity and increased healthcare costs. Several studies have shown racial and ethnic differences in asthma exacerbation rates. We aimed to...