Antonio Chiloeches
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Explore the profile of Antonio Chiloeches including associated specialties, affiliations and a list of published articles.
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24
Citations
514
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Recent Articles
1.
Diaz-Gago S, Vicente-Gutierrez J, Ruiz-Rodriguez J, Calafell J, Alvarez-Alvarez A, Lasa M, et al.
Autophagy
. 2024 Mar;
20(6):1383-1397.
PMID: 38436206
BRAF is the most prevalent mutation in thyroid cancer and correlates with poor prognosis and therapy resistance. Although selective inhibitors of BRAF have been developed, more advanced tumors such as...
2.
Cilleros-Rodriguez D, Toledo-Lobo M, Martinez-Martinez D, Baquero P, Angulo J, Chiloeches A, et al.
Biochim Biophys Acta Mol Basis Dis
. 2023 Aug;
1870(1):166851.
PMID: 37611675
Protein kinase D (PKD) family members play controversial roles in prostate cancer (PC). Thus, PKD1 is nearly absent in advanced tumours, where PKD2 and PKD3 are upregulated. Additionally, consequences of...
3.
Jimenez-Mora E, Gallego B, Diaz-Gago S, Lasa M, Baquero P, Chiloeches A
Int J Mol Sci
. 2021 Jul;
22(11).
PMID: 34204950
The dysregulation of autophagy is important in the development of many cancers, including thyroid cancer, where BRAF is a main oncogene. Here, we analyse the effect of BRAF inhibition on...
4.
Martinez-Martinez D, Toledo Lobo M, Baquero P, Ropero S, Angulo J, Chiloeches A, et al.
Cancers (Basel)
. 2021 Apr;
13(5).
PMID: 33800291
Dual specificity phosphatase 1 (DUSP1) is crucial in prostate cancer (PC), since its expression is downregulated in advanced carcinomas. Here, we investigated DUSP1 effects on the expression of mesenchymal marker...
5.
Martinez-Martinez D, Soto A, Gil-Araujo B, Gallego B, Chiloeches A, Lasa M
Food Chem Toxicol
. 2018 Dec;
124:273-279.
PMID: 30552915
Resveratrol is a polyphenol with chemopreventive properties against prostate cancer; however, the mechanisms underlying its actions are not completely understood. Previously, we demonstrated that DUSP1 induces apoptosis in prostate cancer...
6.
Martin-Sanchez P, Luengo A, Griera M, Orea M, Lopez-Olaneta M, Chiloeches A, et al.
FASEB J
. 2017 Oct;
32(2):920-934.
PMID: 29054855
Ras proteins regulate cell survival, growth, differentiation, blood pressure, and fibrosis in some organs. We have demonstrated that H- ras gene deletion produces mice hypotension via a soluble guanylate cyclase-protein...
7.
Rodriguez-Alvarez F, Jimenez-Mora E, Caballero M, Gallego B, Chiloeches A, Toro M
Mol Cell Biochem
. 2015 Oct;
411(1-2):253-60.
PMID: 26472731
Somatostatin (SST) is one of the main regulators of thyroid function. It acts by binding to its receptors, which lead to the dissociation of G proteins into Gαi and Gβγ...
8.
Baquero P, Jimenez-Mora E, Santos A, Lasa M, Chiloeches A
Mol Carcinog
. 2015 Sep;
55(11):1639-1654.
PMID: 26392228
The epithelial-mesenchymal transition (EMT) is a crucial process in tumour progression, by which epithelial cells acquire a mesenchymal phenotype, increasing its motility and the ability to invade distant sites. Here,...
9.
Gil-Araujo B, Toledo Lobo M, Gutierrez-Salmeron M, Gutierrez-Pitalua J, Ropero S, Angulo J, et al.
Mol Oncol
. 2013 Oct;
8(1):27-38.
PMID: 24080497
Dual specificity phosphatase 1 (DUSP1) and the transcription factor NF-κB are implicated in prostate cancer since their expression levels are altered along this disease, although there are no evidences up...
10.
Baquero P, Sanchez-Hernandez I, Jimenez-Mora E, Orgaz J, Jimenez B, Chiloeches A
Cancer Lett
. 2013 Feb;
335(1):232-41.
PMID: 23435375
BRAF is a main oncogene in human thyroid cancer. Here, we show that BRAF depletion by siRNA or inhibition of its activity by treatment with BRAF inhibitor PLX4720 decreases migration...