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Antonella Ferrante

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Citations 364
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Recent Articles
11.
Ferrante A, Pezzola A, Matteucci A, Di Biase A, Attorri L, Armida M, et al.
Neurobiol Dis . 2017 Oct; 110:1-11. PMID: 29079454
Niemann-Pick C is a fatal neurovisceral disorder caused, in 95% of cases, by mutation of NPC1 gene. Therapeutic options are extremely limited and new "druggable" targets are highly warranted. We...
12.
Chiodi V, Ferrante A, Ferraro L, Potenza R, Armida M, Beggiato S, et al.
J Neurochem . 2015 Nov; 136(5):907-17. PMID: 26526685
Adenosine A2A receptors (A2 A Rs) and cannabinoid CB1 receptors (CB1 Rs) are highly expressed in the striatum, where they functionally interact and form A2A /CB1 heteroreceptor complexes. We investigated...
13.
De Filippis B, Valenti D, Chiodi V, Ferrante A, de Bari L, Fiorentini C, et al.
Eur Neuropsychopharmacol . 2015 Apr; 25(6):889-901. PMID: 25890884
Rho GTPases are molecules critically involved in neuronal plasticity and cognition. We have previously reported that modulation of brain Rho GTPases by the bacterial toxin CNF1 rescues the neurobehavioral phenotype...
14.
Ferrante A, Martire A, Pepponi R, Varani K, Vincenzi F, Ferraro L, et al.
Neurobiol Dis . 2014 Aug; 71:193-204. PMID: 25132555
Adenosine A1 receptor (A1R) stimulation exerts beneficial effects in response to various insults to the brain and, although it was found neuroprotective in a lesional model of Huntington's disease (HD),...
15.
Visentin S, De Nuccio C, Bernardo A, Pepponi R, Ferrante A, Minghetti L, et al.
J Neurosci . 2013 Sep; 33(39):15388-93. PMID: 24068806
Niemann-Pick type C1 (NPC1) disease is a rare neurovisceral disorder characterized by intracellular accumulation of unesterified cholesterol, sphingolipids, and other lipids in the lysosomal compartment. A deregulation of lysosomal calcium...
16.
Chiodi V, Mallozzi C, Ferrante A, Chen J, Lombroso P, Di Stasi A, et al.
Neuropsychopharmacology . 2013 Aug; 39(3):569-78. PMID: 23989619
The striatum is a brain area implicated in the pharmacological action of drugs of abuse. Adenosine A2A receptors (A2ARs) are highly expressed in the striatum and mediate, at least in...
17.
Martire A, Pepponi R, Domenici M, Ferrante A, Chiodi V, Popoli P
J Neurochem . 2013 Feb; 125(2):225-35. PMID: 23363456
NMDA receptor-mediated excitotoxicity is thought to play a pivotal role in the pathogenesis of Huntington's disease (HD). The neurotrophin brain-derived neurotrophic factor (BDNF), which is also highly involved in HD...
18.
Potenza R, Armida M, Ferrante A, Pezzola A, Matteucci A, Puopolo M, et al.
J Neurosci Res . 2013 Jan; 91(4):585-92. PMID: 23361938
Caffeine is a nonselective adenosine receptor antagonist; chronic consumption has proved protective toward neurodegenerative diseases such as Parkinson's and Alzheimer's diseases. The present study was designed to determine whether caffeine...
19.
Chiodi V, Uchigashima M, Beggiato S, Ferrante A, Armida M, Martire A, et al.
Neurobiol Dis . 2011 Dec; 45(3):983-91. PMID: 22207189
Cannabinoid CB1 receptors (CB1Rs) are known to be downregulated in patients and in animal models of Huntington's disease (HD). However, the functional meaning of this reduction, if any, is still...
20.
Venerosi A, Martire A, Rungi A, Pieri M, Ferrante A, Zona C, et al.
Mol Nutr Food Res . 2011 Apr; 55(4):541-52. PMID: 21462321
Scope: We hypothesized that chronic supplementation with branched chain amino acids (BCAAs) affects neurobehavioral development in vulnerable gene backgrounds. Methods And Results: A murine model of amyotrophic lateral sclerosis (ALS),...