Antje Hader
Overview
Explore the profile of Antje Hader including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
543
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0
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Recent Articles
1.
Reisser Y, Hornung F, Hader A, Lauf T, Nietzsche S, Loffler B, et al.
Elife
. 2024 Nov;
13.
PMID: 39607755
The telomerase RNA component (Terc) constitutes a non-coding RNA critical for telomerase function, commonly associated with aging and pivotal in immunomodulation during inflammation. Our study unveils heightened susceptibility to pneumonia...
2.
Lauf T, Hader A, Hornung F, Reisser Y, Nietzsche S, Schanz F, et al.
Immun Ageing
. 2024 Nov;
21(1):80.
PMID: 39543713
Ageing is a major risk factor that contributes to increased mortality and morbidity rates during influenza A virus (IAV) infections. Macrophages are crucial players in the defense against viral infections...
3.
Hornung F, Kose-Vogel N, Jourdan Le Saux C, Hader A, Herrmann L, Schulz L, et al.
Aging (Albany NY)
. 2023 Dec;
15(23):13593-13607.
PMID: 38095608
Background: SARS-CoV-2 variants are constantly emerging with a variety of changes in the conformation of the spike protein, resulting in alterations of virus entry mechanisms. Solely omicron variants use the...
4.
Deinhardt-Emmer S, Deshpande S, Kitazawa K, Herman A, Bons J, Rose J, et al.
Aging Dis
. 2023 Sep;
15(3):1398-1415.
PMID: 37728586
During cellular senescence, persistent growth arrest and changes in protein expression programs are accompanied by a senescence-associated secretory phenotype (SASP). In this study, we detected the upregulation of the SASP-related...
5.
Hornung F, Schulz L, Kose-Vogel N, Hader A, Griesshammer J, Wittschieber D, et al.
Int J Obes (Lond)
. 2023 Aug;
47(11):1088-1099.
PMID: 37587162
Objective: Obesity is an independent risk factor for severe influenza virus and COVID-19 infections. There might be an interplay between adipose tissue and respiratory pathogens, although the mechanism is unknown....
6.
Hader A, Schauble S, Gehlen J, Thielemann N, Buerfent B, Schuller V, et al.
Nat Commun
. 2023 Jun;
14(1):3239.
PMID: 37277347
Innate immune responses vary by pathogen and host genetics. We analyze quantitative trait loci (eQTLs) and transcriptomes of monocytes from 215 individuals stimulated by fungal, Gram-negative or Gram-positive bacterial pathogens....
7.
Hader A, Kose-Vogel N, Schulz L, Mlynska L, Hornung F, Hagel S, et al.
Aging Dis
. 2023 May;
14(4):1091-1104.
PMID: 37163442
Respiratory infections pose a significant health problem among elderly individuals, particularly during the COVID-19 pandemic. The increased mortality and morbidity rates among individuals over 65 highlight the criticality of these...
8.
Influenza Virus-Induced Paracrine Cellular Senescence of the Lung Contributes to Enhanced Viral Load
Schulz L, Hornung F, Hader A, Radosa L, Brakhage A, Loffler B, et al.
Aging Dis
. 2023 May;
14(4):1331-1348.
PMID: 37163429
Aging is a major risk factor associated with increased morbidity and mortality rates observed during respiratory infections. In this study, we investigated the role of influenza virus infections in the...
9.
Seif M, Kakoschke T, Ebel F, Bellet M, Trinks N, Renga G, et al.
Sci Transl Med
. 2022 Sep;
14(664):eabh1209.
PMID: 36170447
is a ubiquitous mold that can cause severe infections in immunocompromised patients, typically manifesting as invasive pulmonary aspergillosis (IPA). Adaptive and innate immune cells that respond to are present in...
10.
Zoran T, Seelbinder B, White P, Price J, Kraus S, Kurzai O, et al.
J Fungi (Basel)
. 2022 Feb;
8(2).
PMID: 35205926
Despite available diagnostic tests and recent advances, diagnosis of pulmonary invasive aspergillosis (IPA) remains challenging. We performed a longitudinal case-control pilot study to identify host-specific, novel, and immune-relevant molecular candidates...