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Anthony J Demetris

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Articles 163
Citations 5424
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Recent Articles
11.
Webber S, Chin H, Wilkinson J, Armstrong B, Canter C, Dipchand A, et al.
Am J Transplant . 2023 Aug; 23(12):1893-1907. PMID: 37579817
The aim of this study (CTOTC-09) was to assess the impact of "preformed" (at transplant) donor-specific anti-HLA antibody (DSA) and first year newly detected DSA (ndDSA) on allograft function at...
12.
OLeary J, Farris A, Gebel H, Asrani S, Askar M, Garcia V, et al.
Transplant Direct . 2023 Jul; 9(8):e1500. PMID: 37456590
Methods: We reevaluated allograft biopsies from simultaneous liver-kidney transplant recipients who had both allografts biopsied within 60 d of one another and within 30 d of DSA being positive in...
13.
El Hag M, Kaneku H, Jorgensen D, Zeevi A, Stevenson H, Yadak N, et al.
Clin Transplant . 2023 Apr; 37(8):e14997. PMID: 37096730
Background: Acute antibody mediated rejection is increasingly identified in liver allografts as a unique form of alloimmune injury associated with donor specific antibodies (DSA). This manifests pathologically as microvascular injury...
14.
Tieu R, Zeng Q, Zhao D, Zhang G, Feizi N, Manandhar P, et al.
Sci Immunol . 2023 Apr; 8(82):eadd8454. PMID: 37083450
Our understanding of tissue-resident memory T (T) cell biology has been largely developed from acute infection models in which antigen is cleared and sterilizing immunity is achieved. Less is known...
15.
Hughes C, Nigmet Y, Villanueva F, Chen X, Demetris A, Stolz D, et al.
Transplant Proc . 2023 Mar; 55(2):485-495. PMID: 36878745
Background: Ischemic cholangiopathy is a process of bile duct injury that might result from peribiliary vascular plexus (PBP) thrombosis and remains a dreaded complication in liver transplantation from donors after...
16.
Tang Q, Leung J, Peng Y, Sanchez-Fueyo A, Lozano J, Lam A, et al.
Sci Transl Med . 2022 Nov; 14(669):eabo2628. PMID: 36322627
Promoting immune tolerance to transplanted organs can minimize the amount of immunosuppressive drugs that patients need to take, reducing lifetime risks of mortality and morbidity. Regulatory T cells (T) are...
17.
Lim T, Perpinan E, Londono M, Miquel R, Ruiz P, Kurt A, et al.
J Hepatol . 2022 Sep; 78(1):153-164. PMID: 36087863
Background & Aims: CD4CD25Foxp3 regulatory T cells (Tregs) are essential to maintain immunological tolerance and have been shown to promote liver allograft tolerance in both rodents and humans. Low-dose IL-2...
18.
Hubscher S, Feng S, Gouw A, Haga H, Kang H, Kelly D, et al.
Liver Transpl . 2022 Apr; 28(9):1475-1489. PMID: 35429359
Excellent short-term survival after pediatric liver transplantation (LT) has shifted attention toward the optimization of long-term outcomes. Despite considerable progress in imaging and other noninvasive modalities, liver biopsies continue to...
19.
Squires J, Demetris A
Liver Transpl . 2022 Jan; 28(5):754-755. PMID: 35092345
No abstract available.
20.
Perito E, Persyn E, Bucuvalas J, Martinez M, Mohammad S, Squires J, et al.
Liver Transpl . 2022 Jan; 28(6):1051-1062. PMID: 35029022
Previous single-center, cross-sectional studies have reported a steep increase in the prevalence and severity of fibrosis through 10 to 15 years after pediatric liver transplantation. We report a multicenter study...