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Anpuchchelvi Rajadurai

Explore the profile of Anpuchchelvi Rajadurai including associated specialties, affiliations and a list of published articles. Areas
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Citations 135
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Recent Articles
1.
Poudel K, Ji Z, Njauw C, Rajadurai A, Bhayana B, Sullivan R, et al.
Bioact Mater . 2025 Jan; 46():347-364. PMID: 39834347
Cancer nanovaccines hold the promise for personalization, precision, and pliability by integrating all the elements essential for effective immune stimulation. An effective immune response requires communication and interplay between antigen-presenting...
2.
Rajadurai A, Tsao H
JID Innov . 2024 Feb; 4(2):100248. PMID: 38303762
Keloids are characterized by excessive extracellular collagen and exaggerated scarring. Large-volume lesions can be functionally debilitating, therapeutically intractable, and psychologically devastating. A key barrier to translational momentum for novel antikeloid...
3.
Guhan S, Shaughnessy M, Rajadurai A, Taylor M, Kumar R, Ji Z, et al.
J Invest Dermatol . 2021 Mar; 141(8):2018-2027.e4. PMID: 33745909
Approximately half of melanoma tumors lack a druggable target and are unresponsive to current targeted therapeutics. One proposed approach for treating these therapeutically orphaned tumors is by targeting transcriptional dependencies...
4.
Kang Y, Roh M, Rajadurai S, Rajadurai A, Kumar R, Njauw C, et al.
J Invest Dermatol . 2020 Apr; 140(11):2157-2165. PMID: 32315657
Keloids are reactive or spontaneous fibroproliferative dermal tumors characterized by the exaggerated and uncontrolled accumulation of extracellular collagen. Current approaches to mitigate keloidogenesis are largely procedural in nature. However, a...
5.
Shaughnessy M, Lamuraglia G, Klebanov N, Ji Z, Rajadurai A, Kumar R, et al.
Int J Oncol . 2019 Sep; 55(5):1090-1096. PMID: 31545410
Uveal malignant melanoma (UMM), the most common primary adult intraocular tumor with a marked metastatic potential, is genetically unique and has unfortunately had few treatment breakthroughs. In this study, we...
6.
Kumar R, Njauw C, Reddy B, Ji Z, Rajadurai A, Klebanov N, et al.
Oncogene . 2019 Jan; 38(18):3504-3520. PMID: 30651601
The underlying forces that shape mutational patterns within any type of cancer have been poorly characterized. One of the best preserved exclusionary relationships is that between BRAF(V600E) and NRAS(Q61) in...
7.
Redmond R, Rajadurai A, Udayakumar D, Sviderskaya E, Tsao H
J Invest Dermatol . 2013 Dec; 134(4):1083-1090. PMID: 24335898
Long-wave UVA is the major component of terrestrial UV radiation and is also the predominant constituent of indoor sunlamps, both of which have been shown to increase cutaneous melanoma risk....
8.
Ji Z, Kumar R, Taylor M, Rajadurai A, Marzuka-Alcala A, Chen Y, et al.
Clin Cancer Res . 2013 Jul; 19(16):4383-91. PMID: 23812671
Purpose: For patients with advanced melanoma, primary and secondary resistance to selective BRAF inhibition remains one of the most critically compelling challenges. One rationale argues that novel biologically informed strategies...
9.
Rubio N, Rajadurai A, Held K, Prise K, Liber H, Redmond R
Free Radic Biol Med . 2009 May; 47(3):283-90. PMID: 19409981
Cells subjected to various forms of stress have been shown to induce bystander responses in nontargeted cells, thus extending the stress response to a larger population. However, the mechanism(s) of...
10.
Valencia A, Rajadurai A, Carle A, Kochevar I
Free Radic Biol Med . 2006 Dec; 41(11):1704-18. PMID: 17145559
Long wavelength solar UVA radiation stimulates formation of reactive oxygen species (ROS) and prostaglandin E(2) (PGE(2)), which are involved in skin photosensitivity and tumor promotion. High levels of 7-dehydrocholesterol (7-DHC),...