Anouk L van Oosten
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Explore the profile of Anouk L van Oosten including associated specialties, affiliations and a list of published articles.
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6
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867
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Recent Articles
1.
Stuart H, van Oosten A, Radzisheuskaya A, Martello G, Miller A, Dietmann S, et al.
Curr Biol
. 2014 Jan;
24(3):340-6.
PMID: 24462001
Reprogramming of a differentiated cell back to a naive pluripotent identity is thought to occur by several independent mechanisms. Two such mechanisms include NANOG and activated STAT3 (pSTAT3), known master...
2.
van Oosten A, Costa Y, Smith A, Silva J
Nat Commun
. 2012 May;
3:817.
PMID: 22569365
Induced pluripotency depends on cooperativity between expression of defined factors and the culture environment. The latter also determines the pluripotent cell state, that is, naïve or primed. LIF-JAK/STAT3 signalling was...
3.
Theunissen T, Costa Y, Radzisheuskaya A, van Oosten A, Lavial F, Pain B, et al.
Development
. 2011 Oct;
138(22):4853-65.
PMID: 22028025
Pluripotency is a developmental ground state that can be recreated by direct reprogramming. Establishment of pluripotency is crucially dependent on the homeodomain-containing transcription factor Nanog. Compared with other pluripotency-associated genes,...
4.
Theunissen T, van Oosten A, Castelo-Branco G, Hall J, Smith A, Silva J
Curr Biol
. 2011 Jan;
21(1):65-71.
PMID: 21194951
Induced pluripotency requires the expression of defined factors and culture conditions that support the self-renewal of embryonic stem (ES) cells. Small molecule inhibition of MAP kinase (MEK) and glycogen synthase...
5.
Yang J, van Oosten A, Theunissen T, Guo G, Silva J, Smith A
Cell Stem Cell
. 2010 Sep;
7(3):319-28.
PMID: 20804969
The cytokine leukemia inhibitory factor (Lif) sustains self-renewal of mouse embryonic and induced pluripotent stem cells by activating Jak kinase and the transcription factor Stat3. Here we investigate whether Jak/Stat3...
6.
Silva J, Nichols J, Theunissen T, Guo G, van Oosten A, Barrandon O, et al.
Cell
. 2009 Aug;
138(4):722-37.
PMID: 19703398
Pluripotency is generated naturally during mammalian development through formation of the epiblast, founder tissue of the embryo proper. Pluripotency can be recreated by somatic cell reprogramming. Here we present evidence...