Annette T Y Wong
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Explore the profile of Annette T Y Wong including associated specialties, affiliations and a list of published articles.
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20
Citations
227
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Recent Articles
1.
Rangan G, Wong A, Munt A, Zhang J, Saravanabavan S, Louw S, et al.
NEJM Evid
. 2024 Feb;
1(1):EVIDoa2100021.
PMID: 38319283
BACKGROUND: Arginine vasopressin promotes kidney cyst growth in autosomal dominant polycystic kidney disease (ADPKD). Increased water intake reduces arginine vasopressin and urine osmolality and may slow kidney cyst growth. METHODS:...
2.
Sagar P, Saravanabavan S, Munt A, Wong A, Rangan G
J Cardiovasc Dev Dis
. 2021 Nov;
8(11).
PMID: 34821697
Vitamin D secosteroids are intranuclear regulators of cellular growth and suppress the renin-angiotensin system. The aim of this study was to test the hypothesis that the vitamin D receptor agonist,...
3.
Zhang J, Saravanabavan S, Cheng K, Raghubanshi A, Chandra A, Munt A, et al.
PLoS One
. 2021 Apr;
16(4):e0248400.
PMID: 33886581
Augmentation of endogenous nitric oxide (NO) synthesis, either by the classical L-arginine-NO synthase pathway, or the recently discovered entero-salivary nitrate-nitrite-NO system, may slow the progression of autosomal dominant polycystic kidney...
4.
Zhang J, Saravanabavan S, Chandra A, Munt A, Wong A, Harris P, et al.
Am J Pathol
. 2021 Feb;
191(5):902-920.
PMID: 33549515
DNA damage and alterations in DNA damage response (DDR) signaling could be one of the molecular mechanisms mediating focal kidney cyst formation in autosomal dominant polycystic kidney disease (ADPKD). The...
5.
Wong A, Munt A, Allman-Farinelli M, Badve S, Boudville N, Coolican H, et al.
Nutrients
. 2020 Nov;
12(11).
PMID: 33147804
The excess intake of dietary sodium is a key modifiable factor for reducing disease progression in autosomal dominant polycystic kidney disease (ADPKD). The aim of this study was to test...
6.
OBrien K, Saravanabavan S, Zhang J, Wong A, Munt A, Burgess J, et al.
Int J Nephrol Renovasc Dis
. 2020 Apr;
13:53-64.
PMID: 32280260
Background/aim: The natural history of the renal microvasculature changes in PKD is not known. The aim of this study was to test the hypothesis that angiogenesis is coupled with kidney...
7.
Zhang J, Burgess J, Stepanova D, Saravanabavan S, Wong A, Kaldis P, et al.
Lab Invest
. 2020 Jan;
100(5):696-711.
PMID: 31915367
A hallmark of polycystic kidney diseases (PKDs) is aberrant proliferation, which leads to the formation and growth of renal cysts. Proliferation is mediated by cyclin-dependent kinases (Cdks), and the administration...
8.
Zhang J, Saravanabavan S, Munt A, Wong A, Harris D, Harris P, et al.
Expert Rev Mol Med
. 2019 Nov;
21:e6.
PMID: 31767049
Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic kidney disease and is caused by heterozygous germ-line mutations in either PKD1 (85%) or PKD2 (15%). It is characterised...
9.
Sagar P, Zhang J, Luciuk M, Mannix C, Wong A, Rangan G
PLoS One
. 2019 Jan;
14(1):e0209186.
PMID: 30601830
Polycystic kidney disease (PKD) is the most common inherited cause of kidney failure and currently has limited treatment options. Increasing water intake reduces renal cyst growth in the pck rat...
10.
Wong A, Mannix C, Grantham J, Allman-Farinelli M, Badve S, Boudville N, et al.
BMJ Open
. 2018 Jan;
8(1):e018794.
PMID: 29358433
Introduction: Maintaining fluid intake sufficient to reduce arginine vasopressin (AVP) secretion has been hypothesised to slow kidney cyst growth in autosomal dominant polycystic kidney disease (ADPKD). However, evidence to support...