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Annette Plesner

Explore the profile of Annette Plesner including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 441
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Recent Articles
1.
Dahl K, Raun K, Hansen J, Poulsen C, de la Cour C, Clausen T, et al.
J Med Chem . 2024 Dec; 67(24):22342. PMID: 39666588
No abstract available.
2.
Dahl K, Raun K, Hansen J, Poulsen C, de la Cour C, Clausen T, et al.
J Med Chem . 2024 Jul; 67(14):11688-11700. PMID: 38960379
Amylin, a member of the calcitonin family, acts via amylin receptors in the hindbrain and hypothalamus to suppress appetite. Native ligands of these receptors are peptides with short half-lives. Conjugating...
3.
Plesner A, Pedersen F, Hauge A, Bruunsgaard H
HLA . 2023 Oct; 103(1):e15262. PMID: 37867411
HLA-DRB1*03:201 differs from HLA-DRB1*03:01 in exon 3 at codon 178 resulting in a proline to serine substitution.
4.
Plesner A, Hald J, Sengelov H, Bruunsgaard H
HLA . 2022 Oct; 101(2):186-187. PMID: 36300759
HLA-DRB1*08:112 differs from HLA-DRB1*08:01 in exon 2 at amino acid 62; asparagine to lysine substitution.
5.
Hald J, Plesner A, Hauge A, Bruunsgaard H
HLA . 2021 Oct; 99(1):66-67. PMID: 34601828
HLA-DQA1*01:65 differs from HLA-DQA1*01:03 in exon 1 at amino acid -7 a valine to methionine substitution.
6.
Abedini A, Cao P, Plesner A, Zhang J, He M, Derk J, et al.
J Clin Invest . 2018 Jan; 128(2):682-698. PMID: 29337308
Islet amyloidosis is characterized by the aberrant accumulation of islet amyloid polypeptide (IAPP) in pancreatic islets, resulting in β cell toxicity, which exacerbates type 2 diabetes and islet transplant failure....
7.
Tsonkova V, Sand F, Wolf X, Grunnet L, Ringgaard A, Ingvorsen C, et al.
Mol Metab . 2018 Jan; 8:144-157. PMID: 29307512
Objective: To characterize the EndoC-βH1 cell line as a model for human beta cells and evaluate its beta cell functionality, focusing on insulin secretion, proliferation, apoptosis and ER stress, with...
8.
Abedini A, Plesner A, Cao P, Ridgway Z, Zhang J, Tu L, et al.
Elife . 2016 May; 5. PMID: 27213520
Islet amyloidosis by IAPP contributes to pancreatic β-cell death in diabetes, but the nature of toxic IAPP species remains elusive. Using concurrent time-resolved biophysical and biological measurements, we define the...
9.
Plesner A, Ten Holder J, Verchere C
PLoS One . 2014 Aug; 9(8):e102843. PMID: 25101835
Islet alpha- and delta-cells are spared autoimmune destruction directed at beta-cells in type 1 diabetes resulting in an apparent increase of non-beta endocrine cells in the islet core. We determined...
10.
Plesner A, Verchere C
J Transplant . 2012 Jan; 2011:979527. PMID: 22235361
The initial step in successful islet transplantation is procurement of healthy donor islets. Given the limited number of donor pancreata selected for islet isolation and that islets from multiple donors...