Annette Ehrhardt
Overview
Explore the profile of Annette Ehrhardt including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
228
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Tedbury P, Manfredi C, Degenhardt F, Conway J, Horwath M, McCracken C, et al.
FASEB J
. 2023 Oct;
37(11):e23220.
PMID: 37801035
Patients with cystic fibrosis (CF) exhibit pronounced respiratory damage and were initially considered among those at highest risk for serious harm from SARS-CoV-2 infection. Numerous clinical studies have subsequently reported...
2.
Huayamares S, Lokugamage M, Rab R, Da Silva Sanchez A, Kim H, Radmand A, et al.
J Control Release
. 2023 Apr;
357:394-403.
PMID: 37028451
Lipid nanoparticles (LNPs) are a clinically relevant way to deliver therapeutic mRNA to hepatocytes in patients. However, LNP-mRNA delivery to end-stage solid tumors such as head and neck squamous cell...
3.
Rab R, Ehrhardt A, Achyut B, Joshi D, Gilbert-Ross M, Huang C, et al.
Cancer Rep (Hoboken)
. 2022 Oct;
6(2):e1708.
PMID: 36253876
Background: Purine nucleoside phosphorylase (PNP) gene transfer represents a promising approach to treatment of head and neck malignancies. We tested recombinant adenovirus already in phase I/II clinical testing and leading-edge...
4.
Joshi D, Ehrhardt A, Hong J, Sorscher E
Pediatr Pulmonol
. 2019 Nov;
54 Suppl 3:S13-S17.
PMID: 31715091
Small molecules that address fundamental defects underlying cystic fibrosis (CF), including modulators such as the approved drugs ivacaftor, lumacaftor, tezacaftor, and elexacaftor, have advanced dramatically over the past few years...
5.
Ehrhardt A, Chung W, Pyle L, Wang W, Nowotarski K, Mulvihill C, et al.
J Biol Chem
. 2015 Dec;
291(4):1854-1865.
PMID: 26627831
In this study, we present data indicating a robust and specific domain interaction between the cystic fibrosis transmembrane conductance regulator (CFTR) first cytosolic loop (CL1) and nucleotide binding domain 1...
6.
Urinary Retention, Incontinence, and Dysregulation of Muscarinic Receptors in Male Mice Lacking Mras
Ehrhardt A, Wang B, Yung A, Wang Y, Kozlowski P, van Breemen C, et al.
PLoS One
. 2015 Oct;
10(10):e0141493.
PMID: 26516777
Here we show that male, but not female mice lacking expression of the GTPase M-Ras developed urinary retention with distention of the bladder that exacerbated with age but occurred in...
7.
Ehrhardt A, Wang B, Leung M, Schrader J
BMC Neurosci
. 2015 Oct;
16:68.
PMID: 26490652
Background: The molecular mechanisms that determine social behavior are poorly understood. Pheromones play a critical role in social recognition in most animals, including mice, but how these are converted into...
8.
Pyle L, Ehrhardt A, Mitchell L, Fan L, Ren A, Naren A, et al.
Am J Physiol Lung Cell Mol Physiol
. 2011 Jul;
301(4):L587-97.
PMID: 21724857
Modulator compounds intended to overcome disease-causing mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) show significant promise in clinical testing for cystic fibrosis. However, the mechanism(s) of action underlying...
9.
Ehrhardt A, David M, Ehrhardt G, Schrader J
Mol Cell Biol
. 2004 Jul;
24(14):6311-23.
PMID: 15226433
Although GTPases of the Ras family have been implicated in many aspects of the regulation of cells, little is known about the roles of individual family members. Here, we analyzed...
10.
Ehrhardt G, Davis R, Hsu J, Leu C, Ehrhardt A, Cooper M
Proc Natl Acad Sci U S A
. 2003 Nov;
100(23):13489-94.
PMID: 14597715
Fc receptor homolog 4 (FcRH4) is a B cell-specific member of the recently identified family of FcRHs whose intracellular domain contains three potential immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The signaling...