Anne Vral
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Explore the profile of Anne Vral including associated specialties, affiliations and a list of published articles.
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95
Citations
1157
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Recent Articles
1.
Beyls E, De Beul S, Bordon V, Ferster A, Haerynck F, Vral A, et al.
Mutat Res Genet Toxicol Environ Mutagen
. 2025 Mar;
902:503852.
PMID: 40044379
Genetic defects in one of the DNA double strand break (DSB) repair proteins lead to distinct human syndromes with severe clinical manifestations, including impaired neurological and immunological development, cancer proneness...
2.
Duthoo E, Beyls E, Backers L, Gudjonsson T, Huang P, Jonckheere L, et al.
J Exp Med
. 2025 Mar;
222(5).
PMID: 40029331
Ataxia telangiectasia and Rad3-related (ATR) kinase and its interacting protein ATRIP orchestrate the replication stress response. Homozygous splice variants in the ATRIP gene, resulting in ATRIP deficiency, were identified in...
3.
Bucher M, Endesfelder D, Pojtinger S, Baeyens A, Barquinero J, Beinke C, et al.
Sci Rep
. 2025 Feb;
15(1):5485.
PMID: 39952996
In previous RENEB interlaboratory comparisons based on the manual scoring of dicentric chromosomes, a tendency for systematic overestimation for doses > 2.5 Gy was found. However, these exercises included only...
4.
Beyls E, Duthoo E, Backers L, Claes K, De Bruyne M, Pottie L, et al.
J Clin Immunol
. 2025 Feb;
45(1):75.
PMID: 39945898
Human inborn errors of immunity (IEI) represent a diverse group of genetic disorders affecting the innate and/or adaptive immune system. Some IEI entities comprise defects in DNA repair factors, resulting...
5.
Delanghe J, Diana Di Mavungu J, Beerens K, Himpe J, Bostan N, Speeckaert M, et al.
Int J Mol Sci
. 2024 May;
25(9).
PMID: 38732004
Age-related macular degeneration (AMD) is an age-related disorder that is a global public health problem. The non-enzymatic Maillard reaction results in the formation of advanced glycation end products (AGEs). Accumulation...
6.
Nobus O, Parmentier L, Livens P, Muyshondt P, Szewcyk K, Jacobs C, et al.
Biomater Adv
. 2024 Mar;
159:213827.
PMID: 38490018
Chronic suppurative otitis media (CSOM) is often associated with permanent tympanic membrane (TM) perforation and conductive hearing loss. The current clinical gold standard, using autografts and allografts, suffers from several...
7.
Zoteva V, De Meulenaere V, Vanhove C, Leybaert L, Raedt R, Pieters L, et al.
PLoS One
. 2024 Mar;
19(3):e0300552.
PMID: 38489314
Glioblastoma (GB), a highly aggressive primary brain tumor, presents a poor prognosis despite the current standard therapy, including radiotherapy and temozolomide (TMZ) chemotherapy. Tumor microtubes involving connexin 43 (Cx43) contribute...
8.
Dayal R, Beyls E, Vral A, Baeyens A
J Vis Exp
. 2024 Mar;
(204).
PMID: 38465937
The in vitro cytokinesis-block micronucleus (CBMN) assay is a widely used technique in radiobiology research, biological dosimetry, genotoxicity studies, and in vitro radiosensitivity testing. This cytogenetic method is based on...
9.
Zoteva V, De Meulenaere V, De Boeck M, Vanhove C, Leybaert L, Raedt R, et al.
PLoS One
. 2024 Jan;
19(1):e0296360.
PMID: 38165944
Glioblastoma (GB) is the most common and malignant primary brain tumor in adults with a median survival of 12-15 months. The F98 Fischer rat model is one of the most...
10.
De Vlieghere E, Van de Vijver K, Blondeel E, Carpentier N, Ghobeira R, Pauwels J, et al.
Biomater Res
. 2023 Oct;
27(1):104.
PMID: 37853495
Background: Long-term drug evaluation heavily relies upon rodent models. Drug discovery methods to reduce animal models in oncology may include three-dimensional (3D) cellular systems that take into account tumor microenvironment...