Anne Hahn
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Explore the profile of Anne Hahn including associated specialties, affiliations and a list of published articles.
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17
Citations
281
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Recent Articles
1.
Hahn A, Hung G, Ahier A, Dai C, Kirmes I, Forde B, et al.
Cell Metab
. 2024 Aug;
36(12):2528-2541.e11.
PMID: 39173633
In virtually all eukaryotes, the mitochondrial DNA (mtDNA) encodes proteins necessary for oxidative phosphorylation (OXPHOS) and RNAs required for their synthesis. The mechanisms of regulation of mtDNA copy number and...
2.
Gandossi C, Jessop H, Hahn A, Heininger L, Henes J, Radaelli A, et al.
Front Nutr
. 2024 May;
11:1394518.
PMID: 38784130
Autoimmune diseases (ADs) represent a heterogeneous group of conditions affecting 5-10% of the global population. In recent decades, hematopoietic stem cell transplant (HSCT), mainly autologous, has been successfully adopted to...
3.
Dai C, Ng C, Hung G, Kirmes I, Hughes L, Du Y, et al.
Nat Cell Biol
. 2023 Jul;
25(8):1111-1120.
PMID: 37460695
The ability to balance conflicting functional demands is critical for ensuring organismal survival. The transcription and repair of the mitochondrial genome (mtDNA) requires separate enzymatic activities that can sterically compete,...
4.
Hahn A, Pensold D, Bayer C, Tittelmeier J, Gonzalez-Bermudez L, Marx-Blumel L, et al.
Front Cell Dev Biol
. 2020 Aug;
8:639.
PMID: 32793592
Increased life expectancy in modern society comes at the cost of age-associated disabilities and diseases. Aged brains not only show reduced excitability and plasticity, but also a decline in inhibition....
5.
Pensold D, Reichard J, van Loo K, Ciganok N, Hahn A, Bayer C, et al.
Cereb Cortex
. 2020 Mar;
30(7):3921-3937.
PMID: 32147726
The balance of excitation and inhibition is essential for cortical information processing, relying on the tight orchestration of the underlying subcellular processes. Dynamic transcriptional control by DNA methylation, catalyzed by...
6.
Hahn A, Zuryn S
Antioxidants (Basel)
. 2019 Sep;
8(9).
PMID: 31514455
Mitochondria are critical for the energetic demands of virtually every cellular process within nucleated eukaryotic cells. They harbour multiple copies of their own genome (mtDNA), as well as the protein-synthesing...
7.
Hahn A, Zuryn S
Trends Cell Biol
. 2018 Dec;
29(3):227-240.
PMID: 30509558
Mitochondrial genome (mitochondrial DNA, mtDNA) lesions that unbalance bioenergetic and oxidative outputs are an important cause of human disease. A major impediment in our understanding of the pathophysiology of mitochondrial...
8.
Symmank J, Bayer C, Schmidt C, Hahn A, Pensold D, Zimmer-Bensch G
Epigenetics
. 2018 Jun;
13(5):536-556.
PMID: 29912614
Epigenetic mechanisms of gene regulation, including DNA methylation and histone modifications, call increasing attention in the context of development and human health. Thereby, interactions between DNA methylating enzymes and histone...
9.
Hahn A, Salomon J, Leitz D, Feigenbutz D, Korsch L, Lisewski I, et al.
Pflugers Arch
. 2018 Jun;
470(9):1335-1348.
PMID: 29860639
Physiological processes of vital importance are often safeguarded by compensatory systems that substitute for primary processes in case these are damaged by gene mutation. Ca-dependent Cl secretion in airway epithelial...
10.
Pensold D, Symmank J, Hahn A, Lingner T, Salinas-Riester G, Downie B, et al.
Cereb Cortex
. 2017 Nov;
27(12):5696-5714.
PMID: 29117290
The proliferative niches in the subpallium generate a rich cellular variety fated for diverse telencephalic regions. The embryonic preoptic area (POA) represents one of these domains giving rise to the...