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Anne C Pavlick

Explore the profile of Anne C Pavlick including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Veeraraghavan J, Gutierrez C, De Angelis C, Davis R, Wang T, Pascual T, et al.
Clin Cancer Res . 2023 May; 29(16):3101-3109. PMID: 37195235
Purpose: Clinical trials reported 25% to 30% pathologic complete response (pCR) rates in HER2+ patients with breast cancer treated with anti-HER2 therapies without chemotherapy. We hypothesize that a multiparameter classifier...
2.
Prat A, Pascual T, De Angelis C, Gutierrez C, Llombart-Cussac A, Wang T, et al.
J Natl Cancer Inst . 2019 May; 112(1):46-54. PMID: 31037288
Background: Identification of HER2-positive breast cancers with high anti-HER2 sensitivity could help de-escalate chemotherapy. Here, we tested a clinically applicable RNA-based assay that combines ERBB2 and the HER2-enriched (HER2-E) intrinsic...
3.
Rimawi M, De Angelis C, Contreras A, Pareja F, Geyer F, Burke K, et al.
Breast Cancer Res Treat . 2017 Nov; 167(3):731-740. PMID: 29110152
Purpose: Aberrant activation of the PI3K pathway has been implicated in resistance to HER2-targeted therapy, but results of clinical trials are confounded by the co-administration of chemotherapy. We investigated the...
4.
Giuliano M, Hu H, Wang Y, Fu X, Nardone A, Herrera S, et al.
Clin Cancer Res . 2015 May; 21(17):3995-4003. PMID: 26015514
Purpose: To investigate the direct effect and therapeutic consequences of epidermal growth factor receptor 2 (HER2)-targeting therapy on expression of estrogen receptor (ER) and Bcl2 in preclinical models and clinical...
5.
Zhang X, Claerhout S, Prat A, Dobrolecki L, Petrovic I, Lai Q, et al.
Cancer Res . 2013 Jun; 73(15):4885-97. PMID: 23737486
Breast cancer research is hampered by difficulties in obtaining and studying primary human breast tissue, and by the lack of in vivo preclinical models that reflect patient tumor biology accurately....
6.
Rimawi M, Mayer I, Forero A, Nanda R, Goetz M, Rodriguez A, et al.
J Clin Oncol . 2013 Apr; 31(14):1726-31. PMID: 23569315
Purpose: We previously reported the eradication of human epidermal growth factor receptor 2 (HER2)- amplified human xenografts in mice by inhibition of the HER2 pathway with lapatinib and trastuzumab to...