Anne C G Almeida
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Explore the profile of Anne C G Almeida including associated specialties, affiliations and a list of published articles.
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10
Citations
234
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Recent Articles
1.
Yakubu M, Mwangi V, Netto R, Alecrim M, Alves J, Almeida A, et al.
Sci Rep
. 2024 Mar;
14(1):7249.
PMID: 38538661
Malaria is the leading parasitic disease worldwide, with P. vivax being a major challenge for its control. Several studies have indicated metabolomics as a promising tool for combating the disease....
2.
Macedo M, Almeida A, Silva G, Oliveira A, Mwangi V, Shuan A, et al.
Pathogens
. 2023 Jul;
12(7).
PMID: 37513742
In the Amazon, the treatment for is chloroquine plus primaquine. However, this regimen is limited due to the risk of acute hemolytic anemia in glucose-6-phosphate dehydrogenase deficiency. Primaquine is a...
3.
Melo M, Costa M, Filho F, Brito-Sousa J, Almeida A, Monteiro W, et al.
Biomed Pharmacother
. 2022 Sep;
149:112874.
PMID: 36068770
The western Amazon basin is an important endemic area for malaria by P. vivax. In recent years, several reports showed the treatment failure with chloroquine, which can be related to...
4.
Brito M, Baro B, Raiol T, Ayllon-Hermida A, Safe I, Deroost K, et al.
J Infect Dis
. 2020 Jun;
225(7):1274-1283.
PMID: 32556188
Background: The presence of Plasmodium vivax malaria parasites in the human bone marrow (BM) is still controversial. However, recent data from a clinical case and experimental infections in splenectomized nonhuman...
5.
Toda H, Diaz-Varela M, Segui-Barber J, Roobsoong W, Baro B, Garcia-Silva S, et al.
Nat Commun
. 2020 Jun;
11(1):2761.
PMID: 32487994
Plasmodium vivax is the most widely distributed human malaria parasite. Previous studies have shown that circulating microparticles during P. vivax acute attacks are indirectly associated with severity. Extracellular vesicles (EVs)...
6.
Almeida A, Puca M, Figueiredo E, Barbosa L, Salazar Y, Silva E, et al.
Antimicrob Agents Chemother
. 2020 May;
64(7).
PMID: 32366712
Cytochrome P450 (CYP) enzymes are involved in the biotransformation of chloroquine (CQ), but the role of the different profiles of metabolism of this drug in relation to recurrences has not...
7.
Almeida A, Kuehn A, Castro A, Vitor-Silva S, Figueiredo E, Brasil L, et al.
Parasit Vectors
. 2018 Mar;
11(1):194.
PMID: 29558985
Background: Population-based studies conducted in Latin America have shown a high proportion of asymptomatic and submicroscopic malarial infections. Considering efforts aiming at regional elimination, it is important to investigate the...
8.
Brasil L, Rodrigues-Soares F, Santoro A, Almeida A, Kuhn A, Ramasawmy R, et al.
Malar J
. 2018 Feb;
17(1):57.
PMID: 29390987
Background: CYP2D6 pathway mediates the activation of primaquine into active metabolite(s) in hepatocytes. CYP2D6 is highly polymorphic, encoding CYP2D6 isoforms with normal, reduced, null or increased activity. It is hypothesized...
9.
Baro B, Deroost K, Raiol T, Brito M, Almeida A, de Menezes-Neto A, et al.
PLoS Negl Trop Dis
. 2017 Apr;
11(4):e0005365.
PMID: 28384192
No abstract available.
10.
Monteiro W, Val F, Siqueira A, Franca G, Sampaio V, Melo G, et al.
Mem Inst Oswaldo Cruz
. 2014 Aug;
109(5):553-68.
PMID: 25141282
Plasmodium vivax radical cure requires the use of primaquine (PQ), a drug that induces haemolysis in glucose-6-phosphate dehydrogenase deficient (G6PDd) individuals, which further hampers malaria control efforts. The aim of...