Anne-Sophie Dugast
Overview
Explore the profile of Anne-Sophie Dugast including associated specialties, affiliations and a list of published articles.
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38
Citations
2183
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Recent Articles
1.
McArdel S, Dugast A, Hoover M, Bollampalli A, Hong E, Castano Z, et al.
Cancer Immunol Immunother
. 2021 Jul;
70(9):2701-2719.
PMID: 34244816
Recombinant agonists that activate co-stimulatory and cytokine receptors have shown limited clinical anticancer utility, potentially due to narrow therapeutic windows, the need for coordinated activation of co-stimulatory and cytokine pathways...
2.
Rossignol E, Dugast A, Compere H, Cottrell C, Copps J, Lin S, et al.
Cell Rep
. 2021 May;
35(8):109167.
PMID: 34038720
HIV monoclonal antibodies for viral reservoir eradication strategies will likely need to recognize reactivated infected cells and potently drive Fc-mediated innate effector cell activity. We systematically characterize a library of...
3.
Cizmeci D, Lofano G, Rossignol E, Dugast A, Kim D, Cavet G, et al.
Elife
. 2021 Apr;
10.
PMID: 33843586
A minor subset of individuals infected with HIV-1 develop antibody neutralization breadth during the natural course of the infection, often linked to chronic, high-level viremia. Despite significant efforts, vaccination strategies...
4.
Muenchhoff M, Chung A, Roider J, Dugast A, Richardson S, Kloverpris H, et al.
mSphere
. 2020 Dec;
5(6).
PMID: 33361123
A prophylactic HIV vaccine would ideally induce protective immunity prior to sexual debut. Children develop broadly neutralizing antibody (bnAb) responses faster and at higher frequencies than adults, but little is...
5.
Kamoun W, Dugast A, Suchy J, Grabow S, Fulton R, Sampson J, et al.
Mol Cancer Ther
. 2019 Oct;
19(1):270-281.
PMID: 31597714
Combinations of chemotherapy with immunotherapy have seen recent clinical success, including two approvals of anti-PD-1/L1 agents in combination with taxane-based chemotherapy in non-small cell lung cancer and triple-negative breast cancer....
6.
Tam E, Fulton R, Sampson J, Muda M, Camblin A, Richards J, et al.
Sci Transl Med
. 2019 Oct;
11(512).
PMID: 31578241
Tumor necrosis factor receptor 2 (TNFR2) is the alternate receptor for TNF and can mediate both pro- and anti-inflammatory activities of T cells. Although TNFR2 has been linked to enhanced...
7.
Lofano G, Gorman M, Yousif A, Yu W, Fox J, Dugast A, et al.
Sci Immunol
. 2018 Aug;
3(26).
PMID: 30120121
HIV-specific broadly neutralizing antibodies (bNAbs) confer protection after passive immunization, but the immunological mechanisms that drive their development are poorly understood. Structural features of bNAbs indicate that they originate from...
8.
Mabuka J, Dugast A, Muema D, Reddy T, Ramlakhan Y, Euler Z, et al.
Front Immunol
. 2017 Sep;
8:1104.
PMID: 28943879
Immunological events in acute HIV-1 infection before peak viremia (hyperacute phase) may contribute to the development of broadly cross-neutralizing antibodies. Here, we used pre-infection and acute-infection peripheral blood mononuclear cells...
9.
Dugast A, Arnold K, Lofano G, Moore S, Hoffner M, Simek M, et al.
Clin Infect Dis
. 2017 Feb;
64(8):1098-1104.
PMID: 28158448
Background: Understanding the mechanism(s) by which broadly neutralizing antibodies (bNAbs) emerge naturally following infection is crucial for the development of a protective vaccine against human immunodeficiency virus (HIV). Although previous...
10.
He X, Simoneau C, Granoff M, Lunemann S, Dugast A, Shao Y, et al.
J Immunol Methods
. 2016 Apr;
434:53-60.
PMID: 27094484
Despite a growing number of studies investigating the impact of natural killer (NK) cells on HIV-1 pathogenesis, the exact mechanism by which NK cells recognize HIV-1-infected cells and exert immunological...