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Annabelle M Friera

Explore the profile of Annabelle M Friera including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 204
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Recent Articles
1.
Hu X, White K, Olroyd A, DeJesus R, Dominguez A, Dowdle W, et al.
Nat Biotechnol . 2023 May; 42(3):413-423. PMID: 37156915
Genetic engineering of allogeneic cell therapeutics that fully prevents rejection by a recipient's immune system would abolish the requirement for immunosuppressive drugs or encapsulation and support large-scale manufacturing of off-the-shelf...
2.
Hu X, Gattis C, Olroyd A, Friera A, White K, Young C, et al.
Sci Transl Med . 2023 Apr; 15(691):eadg5794. PMID: 37043559
Transplantation of allogeneic pancreatic donor islets has successfully been performed in selected patients with difficult-to-control insulin-dependent diabetes and impaired awareness of hypoglycemia (IAH). However, the required systemic immunosuppression associated with...
3.
Li W, Claypool M, Friera A, Mclaughlin J, Baltgalvis K, Smith I, et al.
PLoS One . 2014 Apr; 9(4):e94032. PMID: 24710205
Numerous human diseases can lead to atrophy of skeletal muscle, and loss of this tissue has been correlated with increased mortality and morbidity rates. Clinically addressing muscle atrophy remains an...
4.
Smith I, Godinez G, Singh B, McCaughey K, Alcantara R, Gururaja T, et al.
FASEB J . 2014 Mar; 28(7):2790-803. PMID: 24671708
Controlled mechanical ventilation (CMV) is associated with the development of diaphragm atrophy and contractile dysfunction, and respiratory muscle weakness is thought to contribute significantly to delayed weaning of patients. Therefore,...
5.
Baltgalvis K, White K, Li W, Claypool M, Lang W, Alcantara R, et al.
Am J Physiol Heart Circ Physiol . 2014 Feb; 306(8):H1128-45. PMID: 24561866
Intermittent claudication is a form of exercise intolerance characterized by muscle pain during walking in patients with peripheral artery disease (PAD). Endothelial cell and muscle dysfunction are thought to be...
6.
Holland S, Powell M, Franci C, Chan E, Friera A, Atchison R, et al.
Cancer Res . 2005 Oct; 65(20):9294-303. PMID: 16230391
A focus of contemporary cancer therapeutic development is the targeting of both the transformed cell and the supporting cellular microenvironment. Cell migration is a fundamental cellular behavior required for the...