Anna V Protasio
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Explore the profile of Anna V Protasio including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Crosnier C, Hokke C, Protasio A, Brandt C, Rinaldi G, Langenberg M, et al.
J Infect Dis
. 2020 Jun;
225(8):1435-1446.
PMID: 32524140
Background: Schistosomiasis is a major global health problem caused by blood-dwelling parasitic worms, which is currently tackled primarily by mass administration of the drug praziquantel. Appropriate drug treatment strategies are...
12.
Wangwiwatsin A, Protasio A, Wilson S, Owusu C, Holroyd N, Sanders M, et al.
PLoS Negl Trop Dis
. 2020 May;
14(5):e0007743.
PMID: 32374726
Schistosomes are parasitic blood flukes that survive for many years within the mammalian host vasculature. How the parasites establish a chronic infection in the hostile bloodstream environment, whilst evading the...
13.
Marelli S, Williamson J, Protasio A, Naamati A, Greenwood E, Deane J, et al.
Elife
. 2020 Apr;
9.
PMID: 32292164
The seminal description of the cellular restriction factor APOBEC3G and its antagonism by HIV-1 Vif has underpinned two decades of research on the host-virus interaction. We recently reported that HIV-1...
14.
Hernandez-Goenaga J, Lopez-Aban J, Protasio A, Vicente Santiago B, Olmo E, Vanegas M, et al.
Front Immunol
. 2019 Nov;
10:2498.
PMID: 31736947
Schistosomiasis is a significant public health problem in sub-Saharan Africa, China, Southeast Asia, and regions of South and Central America affecting about 189 million people. Kunitz-type serine protease inhibitors have...
15.
Protasio A, van Dongen S, Collins J, Quintais L, Ribeiro D, Sessler F, et al.
PLoS Negl Trop Dis
. 2017 May;
11(5):e0005559.
PMID: 28542189
Schistosomes are parasitic helminths that cause schistosomiasis, a disease affecting circa 200 million people, primarily in underprivileged regions of the world. Schistosoma mansoni is the most experimentally tractable schistosome species...
16.
Suttiprapa S, Rinaldi G, Tsai I, Mann V, Dubrovsky L, Yan H, et al.
PLoS Pathog
. 2016 Oct;
12(10):e1005931.
PMID: 27764257
Schistosomiasis is the most important helminthic disease of humanity in terms of morbidity and mortality. Facile manipulation of schistosomes using lentiviruses would enable advances in functional genomics in these and...
17.
Lamolle G, Protasio A, Iriarte A, Jara E, Simon D, Musto H
Genome Biol Evol
. 2016 Jul;
8(8):2312-8.
PMID: 27435793
Eukaryotic genomes are compositionally heterogeneous, that is, composed by regions that differ in guanine-cytosine (GC) content (isochores). The most well documented case is that of vertebrates (mainly mammals) although it...
18.
Wangwiwatsin A, Protasio A
Nat Rev Microbiol
. 2015 Jun;
13(7):401.
PMID: 26075359
This month's Genome Watch highlights studies that investigate links between Wolbachia genotypes and their phenotypes, and explore how Wolbachia adapts to new host environments.
19.
Winter A, Gillan V, Maitland K, Emes R, Roberts B, McCormack G, et al.
BMC Genomics
. 2015 Apr;
16:331.
PMID: 25896062
Background: Filarial nematodes are important pathogens in the tropics transmitted to humans via the bite of blood sucking arthropod vectors. The molecular mechanisms underpinning survival and differentiation of these parasites...
20.
Horn M, Fajtova P, Rojo Arreola L, Ulrychova L, Bartosova-Sojkova P, Franta Z, et al.
PLoS Negl Trop Dis
. 2014 Mar;
8(3):e2766.
PMID: 24676141
Background: Blood flukes (Schistosoma spp.) are parasites that can survive for years or decades in the vasculature of permissive mammalian hosts, including humans. Proteolytic enzymes (proteases) are crucial for successful...