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Anna Sablina

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Articles 18
Citations 331
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Recent Articles
1.
de Laat V, Topal H, Spotbeen X, Talebi A, Dehairs J, Idkowiak J, et al.
Nat Commun . 2024 Oct; 15(1):8540. PMID: 39358362
A spontaneously occurring temperature increase in solid tumors has been reported sporadically, but is largely overlooked in terms of cancer biology. Here we show that temperature is increased in tumors...
2.
Magits W, Steklov M, Jang H, Sewduth R, Florentin A, Lechat B, et al.
EMBO J . 2024 Jun; 43(14):2862-2877. PMID: 38858602
The RAS pathway is among the most frequently activated signaling nodes in cancer. However, the mechanisms that alter RAS activity in human pathologies are not entirely understood. The most prevalent...
3.
Cokelaere C, Dok R, Cortesi E, Zhao P, Sablina A, Nuyts S, et al.
Cell Oncol (Dordr) . 2023 Nov; 47(3):793-818. PMID: 37971644
Purpose: TIPRL1 (target of rapamycin signaling pathway regulator-like 1) is a known interactor and inhibitor of protein phosphatases PP2A, PP4 and PP6 - all pleiotropic modulators of the DNA Damage...
4.
Sewduth R, Carai P, Ivanisevic T, Zhang M, Jang H, Lechat B, et al.
Adv Sci (Weinh) . 2023 Nov; 10(36):e2303367. PMID: 37946677
Blood flow produces shear stress exerted on the endothelial layer of the vessels. Spatial characterization of the endothelial proteome is required to uncover the mechanisms of endothelial activation by shear...
5.
Sheryazdanova A, Dias Amoedo N, Dufour S, Impens F, Rossignol R, Sablina A
Biochim Biophys Acta Mol Basis Dis . 2023 May; 1869(7):166767. PMID: 37245529
Aerobic glycolysis is a hallmark of cancer development, but this dogma has been challenged by reports showing a key role of oxidative phosphorylation (OXPHOS) in cancer cell survival. It has...
6.
Riera-Domingo C, Leite-Gomes E, Charatsidou I, Zhao P, Carra G, Cappellesso F, et al.
Sci Adv . 2023 Mar; 9(12):eadd5028. PMID: 36947620
Endothelial cells (ECs) grant access of disseminated cancer cells to distant organs. However, the molecular players regulating the activation of quiescent ECs at the premetastatic niche (PMN) remain elusive. Here,...
7.
Chiti F, Sablina A
Curr Opin Struct Biol . 2022 Mar; 74:102359. PMID: 35346569
No abstract available.
8.
Meeusen B, Cortesi E, Omella J, Sablina A, Ventura J, Janssens V
Cancer Lett . 2021 Jul; 520:57-67. PMID: 34216687
KRAS-mutant lung adenocarcinomas represent the largest molecular subgroup of non-small cell lung cancers (NSCLC) and are notorious for their dismal survival perspectives. To gain more insights in etiology and therapeutic...
9.
Manzione M, Rombouts J, Steklov M, Pasquali L, Sablina A, Gelens L, et al.
Mol Biol Cell . 2020 Jan; 31(6):419-438. PMID: 31967936
Chromosome segregation during mitosis is antagonistically regulated by the Aurora-B kinase and RepoMan (recruits PP1 onto mitotic chromatin at anaphase)-associated phosphatases PP1/PP2A. Aurora B is overexpressed in many cancers but,...
10.
Gripp K, Schill L, Schoyer L, Stronach B, Bennett A, Blaser S, et al.
Am J Med Genet A . 2019 Dec; 182(3):597-606. PMID: 31825160
The RASopathies are a group of genetic disorders that result from germline pathogenic variants affecting RAS-mitogen activated protein kinase (MAPK) pathway genes. RASopathies share RAS/MAPK pathway dysregulation and share phenotypic...