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Anna Gaertner-Rommel

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Articles 11
Citations 231
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Recent Articles
1.
Gaertner-Rommel A, Tiesmeier J, Jakob T, Strickmann B, Veit G, Bachmann-Mennenga B, et al.
Mol Genet Genomic Med . 2019 Jul; 7(8):e841. PMID: 31293105
Background: Hypertrophic cardiomyopathy (HCM) is a genetic cardiomyopathy with a prevalence of about 1:200. It is characterized by left ventricular hypertrophy, diastolic dysfunction and interstitial fibrosis; HCM might lead to...
2.
Debus J, Milting H, Brodehl A, Kassner A, Anselmetti D, Gummert J, et al.
J Mol Cell Cardiol . 2019 Mar; 129:303-313. PMID: 30885746
Arrhythmogenic right ventricular cardiomyopathy is a heritable cardiac disease causing severe ventricular arrhythmias, heart failure and sudden cardiac death. It is mainly caused by mutations in genes encoding several structural...
3.
Brodehl A, Ebbinghaus H, Gaertner-Rommel A, Stanasiuk C, Klauke B, Milting H
Genet Med . 2018 Sep; 21(5):1246-1247. PMID: 30262925
No abstract available.
4.
Brodehl A, Gaertner-Rommel A, Milting H
Biophys Rev . 2018 Jun; 10(4):983-1006. PMID: 29926427
Increasing usage of next-generation sequencing techniques pushed during the last decade cardiogenetic diagnostics leading to the identification of a huge number of genetic variants in about 170 genes associated with...
5.
Schirmer I, Dieding M, Klauke B, Brodehl A, Gaertner-Rommel A, Walhorn V, et al.
Mol Genet Genomic Med . 2017 Dec; 6(2):288-293. PMID: 29274115
Background: DES mutations cause different cardiac and skeletal myopathies. Most of them are missense mutations. Methods: Using a next-generation sequencing cardiac 174 gene panel, we identified a novel heterozygous in-frame...
6.
Klauke B, Gaertner-Rommel A, Schulz U, Kassner A, Knyphausen E, Laser T, et al.
PLoS One . 2017 Dec; 12(12):e0189489. PMID: 29253866
Cardiomyopathies might lead to end-stage heart disease with the requirement of drastic treatments like bridging up to transplant or heart transplantation. A not precisely known proportion of these diseases are...
7.
Brodehl A, Gaertner-Rommel A, Milting H
Circ Cardiovasc Genet . 2017 Dec; 10(6). PMID: 29212901
No abstract available.
8.
Dieding M, Debus J, Kerkhoff R, Gaertner-Rommel A, Walhorn V, Milting H, et al.
Sci Rep . 2017 Oct; 7(1):13791. PMID: 29062102
Cadherins are calcium dependent adhesion proteins that establish the intercellular mechanical contact by bridging the gap to adjacent cells. Desmoglein-2 (Dsg2) is a specific cadherin of the cell-cell contact in...
9.
Hellenthal N, Gaertner-Rommel A, Klauke B, Paluszkiewicz L, Stuhr M, Kerner T, et al.
Europace . 2017 Oct; 19(11):1881-1890. PMID: 29016939
Aims: Coronary artery disease accounts for the majority of sudden cardiac deaths (SCD) in the older population whereas cardiomyopathies and arrhythmogenic abnormalities predominate in younger SCD victims (<35 years) with...
10.
Brodehl A, Gaertner-Rommel A, Klauke B, Grewe S, Schirmer I, Peterschroder A, et al.
Hum Mutat . 2017 May; 38(8):947-952. PMID: 28493373
Restrictive cardiomyopathy (RCM) is a rare heart disease characterized by diastolic dysfunction and atrial enlargement. The genetic etiology of RCM is not completely known. We identified by a next-generation sequencing...