Ann Van der Jeugd
Overview
Explore the profile of Ann Van der Jeugd including associated specialties, affiliations and a list of published articles.
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17
Citations
586
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Recent Articles
1.
Craeghs L, Callaerts-Vegh Z, Verslegers M, Van der Jeugd A, Govaerts K, Dresselaers T, et al.
Cereb Cortex
. 2021 Dec;
32(16):3525-3541.
PMID: 34902856
Higher-order telencephalic circuitry has been suggested to be especially vulnerable to irradiation or other developmentally toxic impact. This report details the adult effects of prenatal irradiation at a sensitive time...
2.
Ahmed T, Van der Jeugd A, Caillierez R, Buee L, Blum D, DHooge R, et al.
Front Mol Neurosci
. 2020 Nov;
13:570223.
PMID: 33132838
A major goal in diseases is identifying a potential therapeutic agent that is cost-effective and can remedy some, if not all, disease symptoms. In Alzheimer's disease (AD), aggregation of hyperphosphorylated...
3.
Van der Jeugd A, Parra-Damas A, Baeta-Corral R, Soto-Faguas C, Ahmed T, LaFerla F, et al.
Sci Rep
. 2018 Apr;
8(1):6431.
PMID: 29691439
Accumulation of amyloid-β plaques and tau contribute to the pathogenesis of Alzheimer's disease (AD), but it is unclear whether targeting tau pathology by antioxidants independently of amyloid-β causes beneficial effects...
4.
Van der Jeugd A, DHooge R
J Vis Exp
. 2018 Feb;
(131).
PMID: 29443064
Olfactory recognition deficits are suggested to be able to serve as clinical marker to differentiate Alzheimer's disease (AD) subjects from healthy aging groups. For example, olfactory dysfunction in AD can...
5.
Stroobants S, Damme M, Van der Jeugd A, Vermaercke B, Andersson C, Fogh J, et al.
Neurobiol Dis
. 2017 Jul;
106:255-268.
PMID: 28720484
Alpha-mannosidosis is a glycoproteinosis caused by deficiency of lysosomal acid alpha-mannosidase (LAMAN), which markedly affects neurons of the central nervous system (CNS), and causes pathognomonic intellectual dysfunction in the clinical...
6.
Nisbet R, Van der Jeugd A, Leinenga G, Evans H, Janowicz P, Gotz J
Brain
. 2017 Apr;
140(5):1220-1230.
PMID: 28379300
Alzheimer's disease is characterized by the deposition of amyloid-β as extracellular plaques and hyperphosphorylated tau as intracellular neurofibrillary tangles. Tau pathology characterizes not only Alzheimer's disease, but also many other...
7.
Bodea L, Evans H, Van der Jeugd A, Ittner L, Delerue F, Kril J, et al.
Aging Cell
. 2017 Feb;
16(2):377-386.
PMID: 28160413
Age is a critical factor in the prevalence of tauopathies, including Alzheimer's disease. To observe how an aging phenotype interacts with and affects the pathological intracellular accumulation of hyperphosphorylated tau,...
8.
Van der Jeugd A, Vermaercke B, Halliday G, Staufenbiel M, Gotz J
Neurobiol Learn Mem
. 2016 Feb;
130:34-43.
PMID: 26827932
Frontotemporal lobar degeneration (FTLD) is a neurodegenerative disorder, a major subset of which is characterized by the accumulation of abnormal forms of the protein tau, leading to impairments in motor...
9.
Pooters T, Van der Jeugd A, Callaerts-Vegh Z, DHooge R
Brain Res
. 2015 Jan;
1621:294-308.
PMID: 25619550
Spatial learning and memory in rodents represent close equivalents of human episodic declarative memory, which is especially sensitive to cerebral aging, neurodegeneration, and various neuropsychiatric disorders. Many tests and protocols...
10.
Ahmed T, Van der Jeugd A, Blum D, Galas M, DHooge R, Buee L, et al.
Neurobiol Aging
. 2014 Jun;
35(11):2474-2478.
PMID: 24913895
Tau has been implicated in the organization, stabilization, and dynamics of microtubules. In Alzheimer's disease and more than 20 neurologic disorders tau missorting, hyperphosphorylation, and aggregation is a hallmark. They...