Ann E Vernon
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Explore the profile of Ann E Vernon including associated specialties, affiliations and a list of published articles.
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12
Citations
360
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Recent Articles
1.
Yeh E, Belka G, Vernon A, Chen C, Jung J, Chodosh L
Proc Natl Acad Sci U S A
. 2013 Mar;
110(15):6103-8.
PMID: 23520049
The protooncogenes Akt and c-myc each positively regulate cell growth and proliferation, but have opposing effects on cell survival. These oncogenes cooperate to promote tumorigenesis, in part because the prosurvival...
2.
Murai K, Vernon A, Philpott A, Jones P
Dev Biol
. 2007 Oct;
312(1):61-76.
PMID: 17950722
The specification of mesoderm into distinct compartments sharing the same lineage restricted fates is a crucial step occurring during gastrulation, and is regulated by morphogenic signals such as the FGF/MAPK...
3.
Vernon A, Bakewell S, Chodosh L
Rev Endocr Metab Disord
. 2007 Jul;
8(3):199-213.
PMID: 17657606
Breast cancer begins as a localized disease, but has the potential to spread to distant sites within the body. This process--known as metastasis--is the leading cause of death from breast...
4.
Vernon A, Labonne C
Development
. 2006 Aug;
133(17):3359-70.
PMID: 16887825
The neural crest is a population of stem-cell-like precursors found only in vertebrates. Slug, a member of the Snail family of zincfinger transcriptional repressors, is a critical regulator of neural...
5.
Vernon A, Movassagh M, Horan I, Wise H, Ohnuma S, Philpott A
EMBO Rep
. 2006 May;
7(6):643-8.
PMID: 16648822
The proneural protein neurogenin (XNGNR1) drives differentiation of primary neurons in combination with the cyclin-dependent kinase (Cdk) inhibitor Xic1. Differentiation is inhibited by Notch signalling, resulting in a scattered neuronal...
6.
Light W, Vernon A, Lasorella A, Iavarone A, Labonne C
Development
. 2005 Mar;
132(8):1831-41.
PMID: 15772131
Neural crest cells, a population of proliferative, migratory, tissue-invasive stem cells, are a defining feature of vertebrate embryos. These cells arise at the neural plate border during a time in...
7.
Vernon A, Labonne C
Curr Biol
. 2004 Sep;
14(17):R719-21.
PMID: 15341765
Epithelial-mesenchymal transitions are essential for normal embryonic development and for progression of non-invasive tumor cells into malignant, metastatic carcinomas. Twist, an important regulator of morphogenesis in the embryo, has recently...
8.
Richard-Parpaillon L, Cosgrove R, Devine C, Vernon A, Philpott A
Development
. 2004 Apr;
131(11):2577-86.
PMID: 15115752
Cell division and differentiation are largely incompatible but the molecular links between the two processes are poorly understood. Here, we overexpress G1/S phase cyclins and cyclin-dependent kinases in Xenopus embryos...
9.
Vernon A, Philpott A
Gene Expr Patterns
. 2003 Apr;
3(2):179-92.
PMID: 12711547
Several cyclins and cdks have been cloned in Xenopus, but their developmental expression has not been thoroughly examined. We have analyzed the temporal and spatial expression of cdk1, cdk2, cdk4...
10.
Vernon A, Devine C, Philpott A
Development
. 2002 Nov;
130(1):85-92.
PMID: 12441293
We have investigated the role of the cyclin-dependent kinase inhibitor, p27(Xic1), in the coordination of cell cycle exit and differentiation during early neurogenesis. We demonstrate that p27(Xic1) is highly expressed...