Anke Vandekeere
Overview
Explore the profile of Anke Vandekeere including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
280
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0
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Recent Articles
1.
Urrutia A, Mesa-Ciller C, Guajardo-Grence A, Alkan H, Soro-Arnaiz I, Vandekeere A, et al.
Cell Rep
. 2024 Apr;
43(4):114103.
PMID: 38607920
Hypoxia-inducible factor-1α (HIF1α) attenuates mitochondrial activity while promoting glycolysis. However, lower glycolysis is compromised in human clear cell renal cell carcinomas, in which HIF1α acts as a tumor suppressor by...
2.
Wu Q, Hatse S, Kenis C, Fernandez-Garcia J, Altea-Manzano P, Billen J, et al.
Breast Cancer Res Treat
. 2024 Mar;
205(3):555-565.
PMID: 38472594
Purpose: Recent evidence suggests that age-accumulated methylmalonic acid (MMA) promotes breast cancer progression in mice. This study aims to investigate the association between baseline serum MMA concentrations in patients with...
3.
Pilley S, Hennequart M, Vandekeere A, Blagih J, Legrave N, Fendt S, et al.
Sci Adv
. 2023 Sep;
9(36):eadh2023.
PMID: 37672588
Previous studies have revealed a role for proline metabolism in supporting cancer development and metastasis. In this study, we show that many cancer cells respond to loss of attachment by...
4.
Wu Q, Hatse S, Kenis C, Fernandez-Garcia J, Altea-Manzano P, Billen J, et al.
Geroscience
. 2023 Aug;
46(2):1489-1498.
PMID: 37632634
Methylmalonic acid (MMA), a by-product of propionate metabolism, is known to increase with age. This study investigates the potential of serum MMA concentrations as a biomarker for age-related clinical frailty...
5.
Shimobayashi M, Thomas A, Shetty S, Frei I, Wolnerhanssen B, Weissenberger D, et al.
Elife
. 2023 Mar;
12.
PMID: 36920797
Chronically high blood glucose (hyperglycemia) leads to diabetes and fatty liver disease. Obesity is a major risk factor for hyperglycemia, but the underlying mechanism is unknown. Here, we show that...
6.
Iwata R, Casimir P, Erkol E, Boubakar L, Planque M, Gallego Lopez I, et al.
Science
. 2023 Jan;
379(6632):eabn4705.
PMID: 36705539
Neuronal development in the human cerebral cortex is considerably prolonged compared with that of other mammals. We explored whether mitochondria influence the species-specific timing of cortical neuron maturation. By comparing...
7.
Altea-Manzano P, Vandekeere A, Edwards-Hicks J, Roldan M, Abraham E, Lleshi X, et al.
Mol Cell
. 2022 Nov;
82(23):4537-4547.e7.
PMID: 36327975
Inhibition of the electron transport chain (ETC) prevents the regeneration of mitochondrial NAD, resulting in cessation of the oxidative tricarboxylic acid (TCA) cycle and a consequent dependence upon reductive carboxylation...
8.
Liu Y, Vandekeere A, Xu M, Fendt S, Altea-Manzano P
Front Oncol
. 2022 Oct;
12:988626.
PMID: 36226054
Malignant growth is defined by multiple aberrant cellular features, including metabolic rewiring, inactivation of tumor suppressors and the activation of oncogenes. Even though these features have been described as separate...
9.
Rossi M, Altea-Manzano P, Demicco M, Doglioni G, Bornes L, Fukano M, et al.
Nature
. 2022 Aug;
609(7927):E8.
PMID: 36042336
No abstract available.
10.
Rossi M, Altea-Manzano P, Demicco M, Doglioni G, Bornes L, Fukano M, et al.
Nature
. 2022 May;
605(7911):747-753.
PMID: 35585241
Cancer metastasis requires the transient activation of cellular programs enabling dissemination and seeding in distant organs. Genetic, transcriptional and translational heterogeneity contributes to this dynamic process. Metabolic heterogeneity has also...